(Q33920217)

30 July 2017

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title

Signaling: cellular insights into the pathophysiology of bipolar disorder (English)

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30 July 2017

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1 reference

Manji HK

1

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PubMed ID

11018224

30 July 2017

Lenox RH

series ordinal

2

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PubMed ID

11018224

30 July 2017

language of work or name

English

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publication date

1 September 2000

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30 July 2017

Biological Psychiatry

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30 July 2017

48

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30 July 2017

518-530

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30 July 2017

6

1 reference

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Are schizophrenic and bipolar disorders related? A review of family and molecular studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Emergent properties of networks of biological signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Molecular machines integrate coincident synaptic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Molecular clock genes in man and lower animals: possible implications for circadian abnormalities in depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Attenuation of cyclic AMP production by carbamazepine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Enhancement of hippocampal neurogenesis by lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Long-lasting change in the membrane-associated protein kinase C activity in the hippocampal kindled rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: Model for its antimanic action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Subgenual prefrontal cortex abnormalities in mood disorders.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

The calcium second messenger system in bipolar disorders: data supporting new research directions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

A molecular and cellular theory of depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

The cyclic AMP second messenger system in man: the effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Social zeitgebers and biological rhythms. A unified approach to understanding the etiology of depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Receptor-mediated activation of G proteins is increased in postmortem brains of bipolar affective disorder subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Elevated basal and thapsigargin-stimulated intracellular calcium of platelets and lymphocytes from bipolar affective disorder patients measured by a fluorometric microassay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Molecular mechanisms underlying mood stabilization in manic-depressive illness: the phenotype challenge

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Increased adenylyl cyclase type 1 mRNA, but not adenylyl cyclase type 2 in the rat hippocampus following antidepressant treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Anti-bipolar therapy: mechanism of action of lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

A bimodal model of the mechanism of action of lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Lithium and brain signal transduction systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Relationship between Rap1 protein phosphorylation and regulation of Ca2+ transport in platelets: a new approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

G proteins: implications for psychiatry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

In Vivo Evidence that Lithium Inactivates Gi Modulation of Adenylate Cyclase in Brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Increased G alpha q/11 immunoreactivity in postmortem occipital cortex from patients with bipolar affective disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Signal transduction by platelet adenylate cyclase: alterations in depressed patients may reflect impairment in the coordinated integration of cellular signals (coincidence detection).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

The effects of lithium in vitro and ex vivo on adenylate cyclase in brain are exerted by distinct mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Effects of lithium on second messenger systems in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Chronic antidepressant administration alters the subcellular distribution of cyclic AMP-dependent protein kinase in rat frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Effects of lithium in vitro and ex vivo on components of the adenylate cyclase system in membranes from the cerebral cortex of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

A naturally occurring amino acid substitution of the human serotonin 5-HT2A receptor influences amplitude and timing of intracellular calcium mobilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Second messenger-regulated protein kinases in the brain: their functional role and the action of antidepressant drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Reduced [3H]cyclic AMP binding in postmortem brain from subjects with bipolar affective disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Abnormal G protein alpha(s) - and alpha(i2)-subunit mRNA expression in bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Enhanced protein kinase C activity and translocation in bipolar affective disorder brains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Effects of lithium on receptor-mediated activation of G proteins in rat brain cortical membranes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Cyclic AMP responsive element binding protein phosphorylation and DNA binding is decreased by chronic lithium but not valproate treatment of SH-SY5Y neuroblastoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Can antidepressants cause mania and worsen the course of affective illness?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Complexity in biological signaling systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Region-selective effects of long-term lithium and carbamazepine administration on cyclic AMP levels in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Beta-adrenoceptor binding defects in cell lines from families with manic-depressive disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Mood stabilizers have differential effects on endogenous ADP ribosylation in C6 glioma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2800%2900929-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-3223(00)00929-X

1 reference

30 July 2017

1 reference

PubMed ID

11018224