(Q33745706)

29 July 2017

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title

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? (English)

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29 July 2017

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Manji HK

1

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29 July 2017

Moore GJ

series ordinal

2

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29 July 2017

Chen G

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

1 October 1999

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29 July 2017

Biological Psychiatry

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29 July 2017

46

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29 July 2017

7

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29 July 2017

929-940

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The Bcl-2 protein family: arbiters of cell survival

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Bcl-2 promotes regeneration of severed axons in mammalian CNS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Signal transduction by the Wnt family of ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Subgenual prefrontal cortex abnormalities in mood disorders.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

A molecular and cellular theory of depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Neurogenesis in the adult human hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Tyrosine kinase inhibitors and cycloheximide inhibit Li+ protection of cerebellar granule neurons switched to non-depolarizing medium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium inhibits growth in a murine neural precursor cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Initiation and adaptation: a paradigm for understanding psychotropic drug action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Molecular mechanisms underlying mood stabilization in manic-depressive illness: the phenotype challenge

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium delays the radiation-induced apoptotic process in external granule cells of mouse cerebellum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Anti-bipolar therapy: mechanism of action of lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

The AML1/ETO fusion protein activates transcription of BCL-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

A molecular mechanism for the effect of lithium on development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Deciphering the pathways of life and death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

[20] Analysis of altered gene expression by differential display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Induction of apoptosis in HL-60 cells by lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Signal transduction pathways. Molecular targets for lithium's actions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Stress effects on morphology and function of the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Bcl-2 gene family in the nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Antidepressant treatments in the 21st century

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Glial reduction in the subgenual prefrontal cortex in mood disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Lithium: a brake in the rising cost of mental illness.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Bcl-2 family members in the development and degenerative pathologies of the nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Experimental therapeutics of neurodegenerative disorders: unmet needs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

The anatomy of mood disorders--review of structural neuroimaging studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Effects of chronic lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

N-acetylaspartate in neuropsychiatric disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Differential display PCR reveals increased expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase by lithium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Beta-catenin: a key mediator of Wnt signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Apoptosis: unmasking the executioner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2899%2900165-1

10.1016/S0006-3223(99)00165-1

7 January 2021

Identifiers

DOI

1 reference

29 July 2017

1 reference