(Q40975742)

English

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

scientific article published on February 1999

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 September 2017

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex (English)

1 reference

Europe PubMed Central

25 September 2017

Alzheimer's disease

0 references

James R. Woodgett

24

1 reference

Europe PubMed Central

25 September 2017

Ekaterina Rogaeva

13

object named as

E Rogaeva

1 reference

Europe PubMed Central

25 September 2017

Toshitaka Kawarai

10

object named as

T Kawarai

1 reference

Europe PubMed Central

25 September 2017

author name string

M Nishimura

1

1 reference

Europe PubMed Central

25 September 2017

G Yu

2

1 reference

Europe PubMed Central

25 September 2017

G Levesque

3

1 reference

Europe PubMed Central

25 September 2017

D M Zhang

4

1 reference

Europe PubMed Central

25 September 2017

L Ruel

5

1 reference

Europe PubMed Central

25 September 2017

F Chen

6

1 reference

Europe PubMed Central

25 September 2017

P Milman

7

1 reference

Europe PubMed Central

25 September 2017

E Holmes

8

1 reference

Europe PubMed Central

25 September 2017

Y Liang

9

1 reference

Europe PubMed Central

25 September 2017

E Jo

11

1 reference

Europe PubMed Central

25 September 2017

A Supala

12

1 reference

Europe PubMed Central

25 September 2017

D M Xu

14

1 reference

Europe PubMed Central

25 September 2017

C Janus

15

1 reference

Europe PubMed Central

25 September 2017

L Levesque

16

1 reference

Europe PubMed Central

25 September 2017

Q Bi

17

1 reference

Europe PubMed Central

25 September 2017

M Duthie

18

1 reference

Europe PubMed Central

25 September 2017

R Rozmahel

19

1 reference

Europe PubMed Central

25 September 2017

K Mattila

20

1 reference

Europe PubMed Central

25 September 2017

L Lannfelt

21

1 reference

Europe PubMed Central

25 September 2017

D Westaway

22

1 reference

Europe PubMed Central

25 September 2017

H T Mount

23

1 reference

Europe PubMed Central

25 September 2017

P St George-Hyslop

25

1 reference

Europe PubMed Central

25 September 2017

language of work or name

0 references

publication date

1 February 1999

1 reference

Europe PubMed Central

25 September 2017

Nature Medicine

1 reference

Europe PubMed Central

25 September 2017

5

1 reference

Europe PubMed Central

25 September 2017

2

1 reference

Europe PubMed Central

25 September 2017

164-169

1 reference

Europe PubMed Central

25 September 2017

https://scigraph.springernature.com/pub.10.1038/5526

0 references

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

A familial Alzheimer's disease locus on chromosome 1.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Skeletal and CNS defects in Presenilin-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

A molecular mechanism for the effect of lithium on development

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

The Glu318Gly mutation of the presenilin-1 gene does not necessarily cause Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud.

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

1 reference

https://api.crossref.org/works/10.1038%2F5526

21 January 2018

Lithium-induced respecification of pattern in Xenopus laevis embryos

1 reference

https://api.crossref.org/works/10.1038%2F5526

7 January 2021

based on heuristic

inferred from DOI database lookup

Wide range in age of onset for chromosome 1--related familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2F5526

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of increased glycogen synthase kinase-3 activity upon the maturation of the amyloid precursor protein in transfected cells

1 reference

https://api.crossref.org/works/10.1038%2F5526

7 January 2021

based on heuristic

inferred from DOI database lookup

Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin 1

1 reference

https://api.crossref.org/works/10.1038%2F5526

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism for biphasic rel A. NF-kappaB1 nuclear translocation in tumor necrosis factor alpha-stimulated hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2F5526

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40975742&oldid=2128723696"