(Q33920700)

30 July 2017

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Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. (English)

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genome-wide association study

30 July 2017

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author

Gary Saunders

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29

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57

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30 July 2017

64

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30 July 2017

Cornelia M. van Duijn

84

Cornelia M van Duijn

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André Uitterlinden

65

André G Uitterlinden

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Jouke-Jan Hottenga

42

Jouke-Jan Hottenga

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Gonneke Willemsen

67

Gonneke Willemsen

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Andres Metspalu

79

Andres Metspalu

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Jennifer Harrow

38

Jennifer Harrow

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Karen Andersen-Ranberg

25

Karen Andersen-Ranberg

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Mark Lathrop

46

Mark Lathrop

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30 July 2017

19

Erik B van den Akker

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Marianne Nygaard

Marianne Nygaard

16

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Joris Deelen

Joris Deelen

1

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Alberto Montesanto

Alberto Montesanto

51

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Serena Dato

Serena Dato

32

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Karen Davies

Karen Davies

33

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Alexander Viktorin

Alexander Viktorin

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Lavinia Paternoster

Lavinia Paternoster

55

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Giuseppina Rose

Giuseppina Rose

13

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Irene Maeve Rea

Irene Maeve Rea

73

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Marian Beekman

Marian Beekman

2

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Simon P. Mooijaart

Simon P Mooijaart

52

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Patrik K E Magnusson

Patrik Magnusson

80

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Pilar Galan

Pilar Galan

69

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Qihua Tan

Qihua Tan

6

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Kaare Christensen

Kaare Christensen

76

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Maris Alver

24

Maris Alver

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30 July 2017

9

Riin Tamm

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30 July 2017

15

Krista Fischer

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30 July 2017

Christopher P Nelson

22

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Thorkild I.A. Sørensen

70

Thorkild I A Sørensen

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Jeanine Houwing-Duistermaat

30 July 2017

86

Jeanine J Houwing-Duistermaat

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30 July 2017

Carmen Martin-Ruiz

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Nilesh Samani

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Nilesh J Samani

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30 July 2017

43

Albert Hofman

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30 July 2017

60

Naveed Sattar

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30 July 2017

10

Stella Trompet

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30 July 2017

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Dorret I Boomsma

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30 July 2017

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Owen A Ross

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30 July 2017

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Claudio Franceschi

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30 July 2017

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Eco J C de Geus

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30 July 2017

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Almut Nebel

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30 July 2017

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Thomas B L Kirkwood

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Evelin Mihailov

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Bastiaan T Heijmans

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30 July 2017

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P Eline Slagboom

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30 July 2017

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Rudi G J Westendorp

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30 July 2017

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J Wouter Jukema

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30 July 2017

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David J Stott

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30 July 2017

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Stefan Schreiber

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30 July 2017

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Heather J Cordell

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30 July 2017

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Ruud van der Breggen

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30 July 2017

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Diana van Heemst

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30 July 2017

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Anton J M de Craen

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30 July 2017

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Linda Broer

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30 July 2017

Friederike Flachsbart

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Friederike Flachsbart

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30 July 2017

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Stefan Böhringer

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30 July 2017

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Quinta Helmer

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30 July 2017

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Joanna C Collerton

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Jutta Gampe

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30 July 2017

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Bernard Jeune

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30 July 2017

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Ellen A Nohr

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30 July 2017

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Iris Postmus

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30 July 2017

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Giuseppe Passarino

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30 July 2017

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Hélène Blanché

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30 July 2017

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Amke Caliebe

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30 July 2017

Femke-Anouska Heinsen

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Femke-Anouska Heinsen

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30 July 2017

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Ian Ford

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30 July 2017

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Doris Lechner

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Yoichiro Kamatani

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30 July 2017

Hae-Won Uh

3

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30 July 2017

Kristin L Ayers

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30 July 2017

Anna M Bennet

8

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30 July 2017

Daníel F Guðbjartsson

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30 July 2017

Paolina Crocco

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30 July 2017

Marie E Breen

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30 July 2017

Elisa Cevenini

30

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30 July 2017

Paolo Garagnani

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30 July 2017

Palmi V Jonsson

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30 July 2017

Susan E Mcnerlan

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30 July 2017

Anne Murphy

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30 July 2017

Stefano Salvioli

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30 July 2017

Hreinn Stefánsson

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30 July 2017

Kári Stefánsson

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30 July 2017

Lene Christiansen

82

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30 July 2017

31 March 2014

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30 July 2017

Human Molecular Genetics

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30 July 2017

23

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30 July 2017

16

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30 July 2017

4420-4432

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Systematic identification of trans eQTLs as putative drivers of known disease associations

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Annotation of functional variation in personal genomes using RegulomeDB

5 July 2018

1 reference

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

5 July 2018

1 reference

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genetic signatures of exceptional longevity in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

How to deal with the early GWAS data when imputing and combining different arrays is necessary

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Non-coding RNAs in human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genomics of human longevity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Familial longevity is marked by enhanced insulin sensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Biological, clinical and population relevance of 95 loci for blood lipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

LocusZoom: regional visualization of genome-wide association scan results

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

Genetics and beyond--the transcriptome of human monocytes and disease susceptibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103672

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

5 July 2018

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

5 July 2018

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Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.

5 July 2018

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5 July 2018

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Association of FOXO3A variation with human longevity confirmed in German centenarians

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Inequalities in healthy life years in the 25 countries of the European Union in 2005: a cross-national meta-regression analysis

5 July 2018

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Hallmark features of immunosenescence are absent in familial longevity.

21 January 2018

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The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900

21 January 2018

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Genetic influence on human lifespan and longevity.

21 January 2018

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21 January 2018

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Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?

21 January 2018

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A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals

21 January 2018

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Lower systolic blood pressure is associated with greater mortality in people aged 85 and older.

21 January 2018

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Speed-bumps ahead for the genetics of later-life diseases

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24688116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDU139

1 reference

30 July 2017

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30 July 2017

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