(Q33925653)

30 July 2017

title

Inactivity of human β,β-carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment (English)

1 reference

30 July 2017

Binxing Li

1

1 reference

30 July 2017

Preejith P Vachali

2

1 reference

30 July 2017

Aruna Gorusupudi

3

1 reference

30 July 2017

Zhengqing Shen

4

1 reference

30 July 2017

Hassan Sharifzadeh

5

1 reference

30 July 2017

Brian M Besch

6

1 reference

30 July 2017

Kelly Nelson

7

1 reference

30 July 2017

Madeleine M Horvath

8

1 reference

30 July 2017

Jeanne M Frederick

9

1 reference

30 July 2017

Wolfgang Baehr

10

1 reference

30 July 2017

Paul S Bernstein

11

1 reference

30 July 2017

language of work or name

English

0 references

publication date

30 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

111

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30 July 2017

issue

28

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30 July 2017

page(s)

10173-10178

1 reference

Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3

30 July 2017

cites work

1 reference

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Substrate specificity of purified recombinant human β-carotene 15,15'-oxygenase (BCO1)

5 July 2018

1 reference

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Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Surface plasmon resonance (SPR) studies on the interactions of carotenoids and their binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification of StARD3 as a lutein-binding protein in the macula of the primate retina

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and β-cryptoxanthin by ferret carotene-9',10'-monooxygenase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Biosensor-based fragment screening using FastStep injections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Studies on the singlet oxygen scavenging mechanism of human macular pigment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification of the yellow skin gene reveals a hybrid origin of the domestic chicken

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Xanthophylls are preferentially taken up compared with beta-carotene by retinal cells via a SRBI-dependent mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

In vitro and in vivo characterization of retinoid synthesis from beta-carotene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Transport and retinal capture of lutein and zeaxanthin with reference to age-related macular degeneration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification and metabolic transformations of carotenoids in ocular tissues of the Japanese quail Coturnix japonica

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Structural and biological aspects of carotenoid cleavage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Macular pigment: a review of current knowledge

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification of beta-carotene 15, 15'-monooxygenase as a peroxisome proliferator-activated receptor target gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Expression of beta-carotene 15,15' monooxygenase in retina and RPE-choroid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Carotenoid bioavailability and bioconversion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Peroxisome proliferator-activated receptors: nuclear control of metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Macular pigment and age related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification of lutein and zeaxanthin oxidation products in human and monkey retinas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

A one year study of the macular pigment: the effect of 140 days of a lutein supplement.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Mechanism of carotenoid cleavage to retinoids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Genetic variation in the beta, beta-carotene-9', 10'-dioxygenase gene and association with fat colour in bovine adipose tissue and milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Characterization of a novel carotenoid cleavage dioxygenase from plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Cloning and characterisation of a maize carotenoid cleavage dioxygenase (ZmCCD1) and its involvement in the biosynthesis of apocarotenoids with various roles in mutualistic and parasitic interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Functional characterization of FaCCD1: a carotenoid cleavage dioxygenase from strawberry involved in lutein degradation during fruit ripening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Functional analysis of the beta and epsilon lycopene cyclase enzymes of Arabidopsis reveals a mechanism for control of cyclic carotenoid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402526111

Macular pigment in donor eyes with and without AMD: a case-control study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104844

Macular pigment in Henle fiber membranes: a model for Haidinger's brushes

29 October 2018

1 reference

12 December 2020

Preliminary identification of the human macular pigment

1 reference

12 December 2020

The prime role of HDL to transport lutein into the retina: evidence from HDL-deficient WHAM chicks having a mutant ABCA1 transporter

1 reference

12 December 2020

CMO1 deficiency abolishes vitamin A production from beta-carotene and alters lipid metabolism in mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1402526111

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference