(Q36216420)

12 August 2017

Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression (English)

1 reference

12 August 2017

Preethi Chander

1

1 reference

12 August 2017

Susan Gentleman

series ordinal

2

1 reference

12 August 2017

Eugenia Poliakov

series ordinal

3

1 reference

12 August 2017

T Michael Redmond

series ordinal

4

1 reference

12 August 2017

language of work or name

English

0 references

publication date

28 June 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

1 reference

12 August 2017

36

1 reference

12 August 2017

30552-30559

1 reference

Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Aromatic lipophilic spin traps effectively inhibit RPE65 isomerohydrolase activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

MarkUs: a server to navigate sequence-structure-function space

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Structural Insights into Maize Viviparous14, a Key Enzyme in the Biosynthesis of the Phytohormone Abscisic Acid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Retinol dehydrogenases (RDHs) in the visual cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Membrane-binding and enzymatic properties of RPE65

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

The SWISS-MODEL Repository and associated resources

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Structural and biological aspects of carotenoid cleavage

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

RPE65 is the isomerohydrolase in the retinoid visual cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

The structure of a retinal-forming carotenoid oxygenase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

The Uppsala Electron-Density Server

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Dark adaptation and the retinoid cycle of vision

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Biochemistry of visual pigment regeneration: the Friedenwald lecture.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Reduced surface: an efficient way to compute molecular surfaces

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436303

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

1 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.364596

Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.364596

PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.364596

The role of aromatic phenylalanine residues in binding carotenoid to light-harvesting model and wild-type complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.364596

Understanding the functional roles of amino acid residues in enzyme catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.364596

Rapid, simultaneous determination of isomers of retinal, retinal oxime and retinol by high-performance liquid chromatography

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22745121

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.364596

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22745121

1 reference