(Q33930675)

30 July 2017

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title

Reactive oxygen radicals in signaling and damage in the ischemic brain (English)

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30 July 2017

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Chan PH

1

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30 July 2017

publication date

1 January 2001

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Journal of Cerebral Blood Flow & Metabolism

30 July 2017

published in

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30 July 2017

volume

21

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30 July 2017

issue

1

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30 July 2017

page(s)

2-14

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Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

30 July 2017

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Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

21 January 2018

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Cerebral ischemia/reperfusion increases endothelial nitric oxide synthase levels by an indomethacin-sensitive mechanism

21 January 2018

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

21 January 2018

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

21 January 2018

1 reference

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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Role of oxidants in ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Regulation of gene expression by reactive oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

A novel neuronal messenger molecule in brain: the free radical, nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Brain injury after perinatal hypoxia-ischemia is exacerbated in copper/zinc superoxide dismutase transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

APE/Ref-1 responses to ischemia in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

21 January 2018

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Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Selective sparing of NADPH-diaphorase neurons in neonatal hypoxia-ischemia

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Genetic transformation of mouse embryos by microinjection of purified DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Alteration of protein kinase C activity after transient focal cerebral ischemia in mice using in vitro [3H]phorbol-12,13-dibutyrate binding autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Neuronal and endothelial nitric oxide synthase gene knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Bright and dark sides of nitric oxide in ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Expression of c-fos mRNA after a mild focal cerebral ischemia in SOD-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Prolonged expression of hsp70 mRNA following transient focal cerebral ischemia in transgenic mice overexpressing CuZn-superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Effects of nitric oxide synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Reduction of apurinic/apyrimidinic endonuclease expression after transient global cerebral ischemia in rats: implication of the failure of DNA repair in neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Amelioration of hippocampal neuronal damage after global ischemia by neuronal overexpression of BCL-2 in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Expression of hsp70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

NMDA-dependent superoxide production and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Human copper-containing superoxide dismutase of high molecular weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Early decrease in apurinic/apyrimidinic endonuclease is followed by DNA fragmentation after cold injury-induced brain trauma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Overexpression of CuZn-Superoxide Dismutase Reduces Hippocampal Injury After Global Ischemia in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Mitochondria in neurodegeneration: bioenergetic function in cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Requirement for superoxide in excitotoxic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Cytochrome C is released from mitochondria into the cytosol after cerebral anoxia or ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Redox signaling and the emerging therapeutic potential of thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Multiple molecular penumbras after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Potentiation of nitric oxide formation following bilateral carotid occlusion and focal cerebral ischemia in the rat: in vivo detection of the nitric oxide radical by electron paramagnetic resonance spin trapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Ischemic Stroke Injury Is Reduced in Mice Lacking a Functional NADPH Oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Role of neuronal and endothelial nitric oxide synthase in nitric oxide generation in the brain following cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Neuron-specific transgene expression of Bcl-XL but not Bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Oxygen-glucose deprivation induces inducible nitric oxide synthase and nitrotyrosine expression in cerebral endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Spreading depression-induced expression of c-fos and cyclooxygenase-2 in transgenic mice that overexpress human copper/zinc-superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200101000-00002

10.1097/00004647-200101000-00002

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

30 July 2017

1006458461

0 references

1 reference