(Q33934140)

30 July 2017

title

Aligning mouse models of asthma to human endotypes of disease (English)

1 reference

30 July 2017

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Matthew E Poynter

4

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author name string

Rebecca A Martin

series ordinal

1

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30 July 2017

Samantha R Hodgkins

series ordinal

2

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30 July 2017

Anne E Dixon

series ordinal

3

1 reference

30 July 2017

publication date

9 May 2014

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30 July 2017

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30 July 2017

volume

19

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30 July 2017

issue

6

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30 July 2017

page(s)

823-833

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The many faces of asthma in obesity

30 July 2017

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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IL-17A inhibits airway reactivity induced by respiratory syncytial virus infection during allergic airway inflammation

28 July 2018

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A global perspective in asthma: from phenotype to endotype

28 July 2018

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Stratified approaches to the treatment of asthma

28 July 2018

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The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin

28 July 2018

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Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?

28 July 2018

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Lebrikizumab in the personalized management of asthma

28 July 2018

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Induction and molecular signature of pathogenic TH17 cells

28 July 2018

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Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling

28 July 2018

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Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.

28 July 2018

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Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

28 July 2018

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Untangling asthma phenotypes and endotypes

28 July 2018

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Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

28 July 2018

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Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice

28 July 2018

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Severe asthma: from characteristics to phenotypes to endotypes

28 July 2018

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Severe asthma: advances in current management and future therapy

28 July 2018

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The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.

28 July 2018

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Models and approaches to understand the role of airway remodelling in disease.

28 July 2018

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Lebrikizumab treatment in adults with asthma

28 July 2018

1 reference

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The naive airway hyperresponsiveness of the A/J mouse is Kit-mediated

28 July 2018

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The increasing challenge of discovering asthma drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Animal models of asthma: value, limitations and opportunities for alternative approaches

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Invariant NKT cells are required for airway inflammation induced by environmental antigens

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Insights into asthmatic airway remodelling through murine models

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

T(H)17 cells in asthma and inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Fate mapping of IL-17-producing T cells in inflammatory responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Glucocorticosteroids: current and future directions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Neutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Apolipoprotein E negatively regulates house dust mite-induced asthma via a low-density lipoprotein receptor-mediated pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

TH17 cells in asthma and COPD.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Overview of changes to asthma guidelines: diagnosis and screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Cluster analysis and clinical asthma phenotypes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Corticosteroids for preventing relapse following acute exacerbations of asthma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Interleukin-17 is a negative regulator of established allergic asthma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Efficacy and Safety of Subcutaneous Omalizumab vs Placebo as Add-on Therapy to Corticosteroids for Children and Adults With Asthma

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Dupilumab in persistent asthma with elevated eosinophil levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

A large subgroup of mild-to-moderate asthma is persistently noneosinophilic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

From phenotypes to endotypes to asthma treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-gamma and TLR4/MyD88 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Th17 immunity in patients with allergic asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

The outer wall of small airways is a major site of remodeling in fatal asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Nitrogen dioxide promotes allergic sensitization to inhaled antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Prevention and reversal of pulmonary inflammation and airway hyperresponsiveness by dexamethasone treatment in a murine model of asthma induced by house dust

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Early immunological response to German cockroach frass exposure induces a Th2/Th17 environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: effect of intratracheal treatment of fluticasone propionate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Short-term cigarette smoke exposure enhances allergic airway inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Nebulized anti-IL-13 monoclonal antibody Fab' fragment reduces allergen-induced asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Obesity and asthma: lessons from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FRESP.12315

Interleukin 13 and the evolution of asthma therapy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107015

Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes

29 October 2018

1 reference

12 December 2020

Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice

1 reference

12 December 2020

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

1 reference

12 December 2020

Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse

1 reference

12 December 2020

Cigarette smoke dissociates inflammation and lung remodeling in OVA-sensitized and challenged mice

1 reference

12 December 2020

Endurance training damages small airway epithelium in mice

1 reference

12 December 2020

Winter sports athletes: long-term effects of cold air exposure

1 reference

12 December 2020

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice

1 reference

12 December 2020

Transcription factors GATA-3 and RORγt are important for determining the phenotype of allergic airway inflammation in a murine model of asthma

1 reference

12 December 2020

Interacting genetic loci cause airway hyperresponsiveness

1 reference

12 December 2020

Repeated exposure to low-dose diesel exhaust after allergen challenge exaggerates asthmatic responses in mice

1 reference

12 December 2020

Identifiers

DOI

10.1111/RESP.12315

1 reference

30 July 2017

1 reference

30 July 2017

1 reference