(Q33934350)

30 July 2017

title

The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression (English)

1 reference

30 July 2017

Shiuan Chen

1

1 reference

30 July 2017

Jingjing Ye

series ordinal

2

1 reference

30 July 2017

Ikuko Kijima

series ordinal

3

1 reference

30 July 2017

Dean Evans

series ordinal

4

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 June 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

107

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30 July 2017

issue

24

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30 July 2017

page(s)

11032-11037

1 reference

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines.

30 July 2017

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5 July 2018

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5 July 2018

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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

5 July 2018

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5 July 2018

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Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma

5 July 2018

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CCAAT/enhancer binding protein delta up-regulates aromatase promoters I.3/II in breast cancer epithelial cells

5 July 2018

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5 July 2018

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5 July 2018

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The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells

5 July 2018

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5 July 2018

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Histone deacetylase inhibitors: overview and perspectives

5 July 2018

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Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.

5 July 2018

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5 July 2018

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5 July 2018

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Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

5 July 2018

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Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells

5 July 2018

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Aromatase destabilizer: novel action of exemestane, a food and drug administration-approved aromatase inhibitor

5 July 2018

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Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor

5 July 2018

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Grape seed extract is an aromatase inhibitor and a suppressor of aromatase expression

5 July 2018

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The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance.

5 July 2018

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5 July 2018

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5 July 2018

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Bone loss and the aromatase inhibitors

5 July 2018

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Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer.

5 July 2018

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

5 July 2018

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The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters

5 July 2018

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The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

5 July 2018

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Regulation of aromatase promoter activity in human breast tissue by nuclear receptors

5 July 2018

1 reference

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Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

5 July 2018

1 reference

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Down-regulation of promoter 1.3 activity of the human aromatase gene in breast tissue by zinc-finger protein, snail (SnaH)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Identification and characterization of a cAMP-responsive element in the region upstream from promoter 1.3 of the human aromatase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Modulation of aromatase expression in the breast tissue by ERR alpha-1 orphan receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Presence of alternatively spliced transcripts of aromatase gene in human breast cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

A unique aromatase (P-450AROM) mRNA formed by alternative use of tissue-specific exons 1 in human skin fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890707

A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1000917107

Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1000917107

A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1000917107

Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor-dependent human lung cancer cells

21 January 2018

1 reference

12 December 2020

Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture

1 reference

12 December 2020

Aromatase activity in normal breast and breast tumor tissues: in vivo and in vitro studies

1 reference

12 December 2020

A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription

1 reference

12 December 2020

Aberrant expression of aromatase in breast cancer tissues

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1000917107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference