(Q33936852)

30 July 2017

title

The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein (English)

1 reference

30 July 2017

main subject

Wiskott-Aldrich syndrome

1 reference

1

Daisy W Leung

1 reference

30 July 2017

Michael K Rosen

2

1 reference

30 July 2017

language of work or name

English

0 references

publication date

8 April 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

102

1 reference

30 July 2017

issue

16

1 reference

30 July 2017

page(s)

5685-5690

1 reference

NMR View: A computer program for the visualization and analysis of NMR data

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Allosteric determinants in guanine nucleotide-binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Rho GTPases in cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

The regulation of actin remodeling during T-cell-APC conjugate formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

The guanine nucleotide-binding switch in three dimensions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Conformational switch and role of phosphorylation in PAK activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Flipping the switch: the structural basis for signaling through the CRIB motif

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

GTPases: a family of molecular switches and clocks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Measuring and increasing protein stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556282

Global disruption of the WASP autoinhibited structure on Cdc42 binding. Ligand displacement as a novel method for monitoring amide hydrogen exchange.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0406472102

A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0406472102

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0406472102

Purification of muscle actin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15821030

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15821030

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Thermodynamics of Ras/effector and Cdc42/effector interactions probed by isothermal titration calorimetry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15821030

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0406472102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference