(Q33939529)

30 July 2017

title

Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation (English)

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30 July 2017

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10

Erich Gulbins

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Adriana Haimovitz-Friedman

30 July 2017

13

object named as

Adriana Haimovitz-Friedman

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30 July 2017

Hyunmi Lee

1

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30 July 2017

Jimmy A Rotolo

2

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30 July 2017

Judith Mesicek

3

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30 July 2017

Tuula Penate-Medina

4

1 reference

30 July 2017

Andreas Rimner

5

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30 July 2017

Wen-Chieh Liao

6

1 reference

30 July 2017

Xianglei Yin

7

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30 July 2017

Govind Ragupathi

8

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30 July 2017

Desiree Ehleiter

9

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30 July 2017

Dayong Zhai

11

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30 July 2017

John C Reed

12

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30 July 2017

Zvi Fuks

14

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30 July 2017

Richard Kolesnick

15

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30 July 2017

language of work or name

English

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publication date

13 June 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

6

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30 July 2017

page(s)

e19783

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

13 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide-rich platforms in transmembrane signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Bax distribution into mitochondrial detergent-resistant microdomains is related to ceramide and cholesterol content in postischemic hearts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide-enriched membrane domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

ATM regulates target switching to escalating doses of radiation in the intestines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Caspase-dependent and -independent activation of acid sphingomyelinase signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

On the role of lipid in colicin pore formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Molecular and Cell Biology of Phosphatidylserine and Phosphatidylethanolamine Metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Raft ceramide in molecular medicine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Pathogens: raft hijackers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide enables fas to cap and kill.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Structure of Bax: coregulation of dimer formation and intracellular localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Compartmentalization of ceramide signaling: physical foundations and biological effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Plasma membrane microdomains act as concentration platforms to facilitate intoxication by aerolysin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramides in phospholipid membranes: effects on bilayer stability and transition to nonlamellar phases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Phospholipid synthesis in a membrane fraction associated with mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Apical and basal Forssman antigen in MDCK II cells: a morphological and quantitative study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Lipidic pore formation by the concerted action of proapoptotic BAX and tBID.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Acid sphingomyelinase is indispensable for UV light-induced Bax conformational change at the mitochondrial membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Detergent-resistant membranes are platforms for actinoporin pore-forming activity on intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Ganglioside expression on human malignant melanoma assessed by quantitative immune thin-layer chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Ceramide synthesis in the endoplasmic reticulum can permeabilize mitochondria to proapoptotic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Significant role of ceramide pathway in experimental gastric ulcer formation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Effects of ceramide inhibition on experimental radiation-induced oral mucositis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3113798

CD95 Signaling via Ceramide-rich Membrane Rafts

29 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Ceramide-mediated clustering is required for CD95-DISC formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019783

Conformational change of Bax: a question of life or death

21 January 2018

1 reference

12 December 2020

Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore

1 reference

12 December 2020

Diversity and complexity of ceramide generation after exposure of jurkat leukemia cells to irradiation

1 reference

12 December 2020

Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

1 reference

12 December 2020

Membrane-insertion fragments of Bcl-xL, Bax, and Bid

1 reference

12 December 2020

Lecithin---sphingomyelin ratio in amniotic fluid, as assessed by a modified thin-layer chromatographic method in which a commercial pre-coated plate is used

1 reference

12 December 2020

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ

1 reference

12 December 2020

Different effects of enzyme-generated ceramides and diacylglycerols in phospholipid membrane fusion and leakage

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0019783

Identifiers

DOI

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30 July 2017

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30 July 2017

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