(Q33939720)

30 July 2017

Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance (English)

1 reference

30 July 2017

1 reference

Samer O Abdul-Hay

1

1 reference

30 July 2017

Dongcheul Kang

2

1 reference

30 July 2017

Melinda McBride

3

1 reference

30 July 2017

Lilin Li

4

1 reference

30 July 2017

Ji Zhao

5

1 reference

30 July 2017

Malcolm A Leissring

6

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30 July 2017

language of work or name

English

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publication date

9 June 2011

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30 July 2017

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30 July 2017

6

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30 July 2017

6

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30 July 2017

e20818

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Creative Commons Attribution 4.0 International

30 July 2017

start time

9 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Is the current therapeutic armamentarium in diabetes enough to control the epidemic and its consequences? What are the current shortcomings?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

The inactivation of insulin by tissue extracts; the distribution and properties of insulin inactivating extracts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin degradation: progress and potential

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

28 July 2018

Insulin-degrading enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin degradation: mechanisms, products, and significance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Hyperinsulinemia in transgenic mice carrying multiple copies of the human insulin gene.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin resistance in type II diabetes mellitus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Production of spontaneous diabetic rats by repetition of selective breeding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Insulin and glucagon degradation by the kidney II. Characterization of the mechanisms at neutral pH

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111440

Mechanisms of insulin resistance in experimental hyperinsulinemic dogs

28 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020818

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020818

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020818

Degradation of amylin by insulin-degrading enzyme

21 January 2018

1 reference

12 December 2020

Degradation products of insulin generated by hepatocytes and by insulin protease

1 reference

12 December 2020

Effect of insulinase-inhibitor on hypoglycemic action of insulin

1 reference

12 December 2020

Receptor and postreceptor insulin resistance induced by in vivo hyperinsuiinemia

1 reference

12 December 2020

Effect of 'Insulinase-Inhibitor' on Destruction of Insulin by Intact Mouse

1 reference

12 December 2020

The role of insulinase in the hypoglycemic response to sulfonylureas

1 reference

12 December 2020

Insulinase, insulinase-inhibitors, and diabetes mellitus

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0020818

Identifiers

DOI

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30 July 2017

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30 July 2017

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