(Q33941796)

30 July 2017

title

Discovery research: the scientific challenge of finding new antibiotics (English)

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ORCID Public Data File 2021

30 July 2017

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author name string

David M Livermore

series ordinal

1

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30 July 2017

British Society for Antimicrobial Chemotherapy Working Party on The Urgent Need: Regenerating Antibacterial Drug Discovery and Development

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

23 June 2011

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Journal of Antimicrobial Chemotherapy

30 July 2017

published in

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30 July 2017

volume

66

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30 July 2017

issue

9

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30 July 2017

page(s)

1941-1944

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Why is big Pharma getting out of antibacterial drug discovery?

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Activities of NXL104 combinations with ceftazidime and aztreonam against carbapenemase-Producing Enterobacteriaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Challenges of antibacterial discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Mechanisms of resistance to quinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Alarming β-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Distribution of 16S rRNA methylases among different species of Gram-negative bacilli with high-level resistance to aminoglycosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Mechanisms of RND multidrug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Discovery of a novel and potent class of FabI-directed antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Drug-like properties and the causes of poor solubility and poor permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Type IIA topoisomerase inhibition by a new class of antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Three decades of beta-lactamase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Polymyxins and their novel derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Medicinal plants and antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

A guide to successful bioprospecting: informed by actinobacterial systematics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Molecular engineering approaches to peptide, polyketide and other antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

A Wellcome experiment in seeding drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

Synthesis and spectrum of the neoglycoside ACHN-490

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR262

21 January 2018

Identifiers

DOI

10.1093/JAC/DKR262

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30 July 2017

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