(Q33945989)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

M W VanBrocklin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

A R Guilbeault

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

D L Signorelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

S Brandner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

S L Holmen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

26 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

335-344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma.

5 July 2018

1 reference

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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Tumour cell survival signalling by the ERK1/2 pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Constitutive activation of Raf-1 induces glioma formation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Malignant astrocytic glioma: genetics, biology, and paths to treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The 2007 WHO classification of tumours of the central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Genetic pathways to primary and secondary glioblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The RAF proteins take centre stage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Delivery of short hairpin RNA sequences by using a replication-competent avian retroviral vector.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Astrocyte differentiation states and glioma formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Mutations of the BRAF gene in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Positive and negative regulation of Raf kinase activity and function by phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Negative regulation of the serine/threonine kinase B-Raf by Akt

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Genetic profile of gliosarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Soluble forms of the subgroup A avian leukosis virus [ALV(A)] receptor Tva significantly inhibit ALV(A) infection in vitro and in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The INK4 family of cell cycle inhibitors in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Molecular genetics of brain tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Endothelial apoptosis in Braf-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The new WHO classification of brain tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Spindle-cell glioblastoma or gliosarcoma?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Expression of the class VI intermediate filament nestin in human central nervous system tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

An Enzyme-Linked Immunosorbent Assay for Detecting Avian Leukosis-Sarcoma Viruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Mutation analysis of B-RAF gene in human gliomas.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Essential role for Ras signaling in glioblastoma maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

RAS/RAF pathway activation in gliomas: the result of copy number gains rather than activating mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Desmoplastic spindle-cell glioblastoma or gliosarcoma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Craf-1 protein kinase is essential for mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109991

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

29 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.333

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19855433%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19855433

1 reference