(Q33947378)

30 July 2017

title

Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models (English)

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30 July 2017

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Christopher M Norris

1

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30 July 2017

Inga Kadish

2

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30 July 2017

Eric M Blalock

3

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30 July 2017

Kuey-Chu Chen

4

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30 July 2017

Veronique Thibault

5

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30 July 2017

Nada M Porter

6

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30 July 2017

Philip W Landfield

7

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30 July 2017

Susan D Kraner

8

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30 July 2017

language of work or name

English

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publication date

1 May 2005

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30 July 2017

published in

Journal of Neuroscience

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30 July 2017

volume

25

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30 July 2017

issue

18

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30 July 2017

page(s)

4649-4658

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Ca2+ regulation and gene expression in normal brain aging

30 July 2017

cites work

1 reference

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

5 July 2018

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Calcineurin in memory and bidirectional plasticity

5 July 2018

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Neuropathologic changes in Alzheimer's disease

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture

5 July 2018

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Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

5 July 2018

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5 July 2018

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A novel calcineurin splice variant that modifies calcineurin activity

5 July 2018

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5 July 2018

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5 July 2018

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Calcineurin links Ca2+ dysregulation with brain aging

5 July 2018

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Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

5 July 2018

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Cyclosporin A-sensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes

5 July 2018

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Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

5 July 2018

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5 July 2018

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Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

5 July 2018

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Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions

5 July 2018

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Genetic approaches to memory storage

5 July 2018

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IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

5 July 2018

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Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

5 July 2018

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Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions

5 July 2018

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

5 July 2018

1 reference

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Age-associated changes in Ca(2+)-dependent processes: relation to hippocampal synaptic plasticity

5 July 2018

1 reference

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Reactive astrocytes: cellular and molecular cues to biological function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Aging-associated changes in human brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

5 July 2018

1 reference

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Calcium channel density and hippocampal cell death with age in long-term culture.

5 July 2018

1 reference

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In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

5 July 2018

1 reference

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Inflammation and Alzheimer's disease pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Increase in single L-type calcium channels in hippocampal neurons during aging.

5 July 2018

1 reference

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Molecular profile of reactive astrocytes--implications for their role in neurologic disease

5 July 2018

1 reference

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The calcium rationale in aging and Alzheimer's disease. Evidence from an animal model of normal aging

5 July 2018

1 reference

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Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1

5 July 2018

1 reference

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The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin

5 July 2018

1 reference

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Activation of calcineurin by limited proteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: an electron microscope study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Morphology of the aging brain, human and animal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Identification of an autoinhibitory domain in calcineurin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Spatial relationships between astrocytes and classical plaque components

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Differences in transductional tropism of adenoviral and lentiviral vectors in the rat brainstem

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Transgenic mice expressing the human presenilin 1 gene demonstrate enhanced hippocampal reorganization following entorhinal cortex lesions

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Mechanism of glial activation by S100B: involvement of the transcription factor NFkappaB.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201418

Involvement of calcineurin in Ca2+ paradox-like injury of cultured rat astrocytes

29 October 2018

1 reference

12 December 2020

Survival of hippocampal and cortical neurons in a mixture of MEM+ and B27-supplemented neurobasal medium

1 reference

12 December 2020

Gene-expression profile of the ageing brain in mice

1 reference

12 December 2020

Interpretation, design, and analysis of gene array expression experiments

1 reference

12 December 2020

Neurons, glia, and plasticity in normal brain aging

1 reference

12 December 2020

10.1523/JNEUROSCI.0365-05.2005

Identifiers

DOI

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30 July 2017

1 reference

30 July 2017

1 reference