(Q33948525)

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Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body.

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1 February 2020

Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body (English)

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1 February 2020

Richard Harrison

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1 February 2020

Graham D. Pavitt

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1 February 2020

Daniela Delneri

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1 February 2020

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1 February 2020

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Eleanor J Taylor

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1 February 2020

Susan G Campbell

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1 February 2020

Christian D Griffiths

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1 February 2020

Peter J Reid

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1 February 2020

John W Slaven

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1 February 2020

Paul F G Sims

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1 February 2020

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5 May 2010

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1 February 2020

Molecular Biology of the Cell

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1 February 2020

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1 February 2020

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1 February 2020

2202-2216

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1 February 2020

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11 June 2022

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The Ehrlich pathway for fusel alcohol production: a century of research on Saccharomyces cerevisiae metabolism

1 reference

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A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.

1 reference

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5 July 2018

Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893985

5 July 2018

Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo

1 reference

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Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae

1 reference

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1 reference

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Identification of an alcohol binding site in the first cysteine-rich domain of protein kinase Cdelta

1 reference

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5 July 2018

Localization of the translational guanine nucleotide exchange factor eIF2B: a common theme for GEFs?

1 reference

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5 July 2018

Inhibition of mammalian translation initiation by volatile anesthetics

1 reference

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5 July 2018

Coping with stress: eIF2 kinases and translational control

1 reference

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5 July 2018

eIF2B, a mediator of general and gene-specific translational control

1 reference

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5 July 2018

Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways

1 reference

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5 July 2018

Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control

1 reference

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5 July 2018

Translational regulation of GCN4 and the general amino acid control of yeast

1 reference

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5 July 2018

Inhibition of translation initiation by volatile anesthetics involves nutrient-sensitive GCN-independent and -dependent processes in yeast

1 reference

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Protein serine/threonine phosphatases: life, death, and sleeping.

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eIF2 and the control of cell physiology

1 reference

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The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol

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Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

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TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors

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A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

1 reference

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Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways

1 reference

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5 July 2018

Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity

1 reference

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5 July 2018

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1 reference

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5 July 2018

In yeast, the pseudohyphal phenotype induced by isoamyl alcohol results from the operation of the morphogenesis checkpoint.

1 reference

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

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Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2.

1 reference

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1 reference

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Cajal body dynamics and association with chromatin are ATP-dependent

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1 reference

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A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols

1 reference

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5 July 2018

Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

1 reference

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A role for the Swe1 checkpoint kinase during filamentous growth of Saccharomyces cerevisiae

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1 reference

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Glucose depletion rapidly inhibits translation initiation in yeast

1 reference

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1 reference

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1 reference

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eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

1 reference

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Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.

1 reference

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5 July 2018

Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2

1 reference

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1 reference

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Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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5 July 2018

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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29 October 2018

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10.1091/MBC.E09-11-0962

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444979%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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Europe PubMed Central

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1 February 2020

PubMed publication ID

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1 February 2020

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