(Q36707214)

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Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2

scientific article published on December 1, 1992

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scholarly article

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Europe PubMed Central

15 August 2017

Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2 (English)

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Europe PubMed Central

15 August 2017

protein biosynthesis

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fungal gene expression regulation

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14 September 2022

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T. E. Dever

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14 September 2022

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R. C. Wek

1

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J. F. Cannon

2

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A. G. Hinnebusch

4

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1 December 1992

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full work available at URL

http://mcb.asm.org/cgi/content/abstract/12/12/5700

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14 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1333044/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1333044/pdf/?tool=EBI

Portable Document Format

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14 September 2022

https://europepmc.org/articles/PMC360510

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https://europepmc.org/articles/PMC360510?pdf=render

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14 September 2022

Molecular and Cellular Biology

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15 August 2017

12

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5700-5710

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15 August 2017

12

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Europe PubMed Central

15 August 2017

A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1 reference

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Positive regulation in the general amino acid control of Saccharomyces cerevisiae

1 reference

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Transformation of intact yeast cells treated with alkali cations

1 reference

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The structure of transposable yeast mating type loci

1 reference

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Positive Regulatory Interactions of the HIS4 Gene of Saccharomyces cerevisiae

1 reference

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Vector systems for the expression, analysis and cloning of DNA sequences in S. cerevisiae

1 reference

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A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae

1 reference

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RAS2 of Saccharomyces cerevisiae is required for gluconeogenic growth and proper response to nutrient limitation

1 reference

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30 September 2017

Multiple upstream AUG codons mediate translational control of GCN4.

1 reference

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30 September 2017

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

1 reference

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

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Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase

1 reference

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30 September 2017

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

1 reference

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30 September 2017

A Tn10-lacZ-kanR-URA3 gene fusion transposon for insertion mutagenesis and fusion analysis of yeast and bacterial genes

1 reference

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30 September 2017

Suppressors of the ras2 mutation of Saccharomyces cerevisiae

1 reference

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The role of protein phosphorylation in the hormonal control of enzyme activity

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In yeast, RAS proteins are controlling elements of adenylate cyclase.

1 reference

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Protein serine/threonine kinases

1 reference

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30 September 2017

Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A.

1 reference

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30 September 2017

Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability

1 reference

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30 September 2017

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

1 reference

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Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

1 reference

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30 September 2017

The structure and regulation of protein phosphatases

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The ras oncogene--an important regulatory element in lower eucaryotic organisms.

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The translational activator GCN3 functions downstream from GCN1 and GCN2 in the regulatory pathway that couples GCN4 expression to amino acid availability in Saccharomyces cerevisiae.

1 reference

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Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression

1 reference

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30 September 2017

Complex formation by positive and negative translational regulators of GCN4.

1 reference

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30 September 2017

Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae

1 reference

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30 September 2017

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control

1 reference

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30 September 2017

Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled.

1 reference

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Translational control in mammalian cells

1 reference

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30 September 2017

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

1 reference

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The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase.

1 reference

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Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases

1 reference

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GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae

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The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities.

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Heritable glycogen-storage deficiency in yeast and its induction by ultra-violet light.

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A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinase

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Activity of protein phosphatases against initiation factor-2 and elongation factor-2.

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Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle.

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Role of transfer ribonucleic acids in the regulation of several biosyntheses in Saccharomyces cerevisiae

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The histidine tRNA genes of yeast

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The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

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Purification and characterization of glycogen synthase from a glycogen-deficient strain of Saccharomyces cerevisiae

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The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1333044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the protein kinase dependent on double-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/1333044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation and identification of type 1 and type 2 protein phosphatases from rabbit reticulocyte lysates

1 reference

https://pubmed.ncbi.nlm.nih.gov/1333044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.12.12.5700

1 reference

Europe PubMed Central

15 August 2017

10.1128/MCB.12.12.5700-5710.1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1333044

14 September 2022

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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