(Q33948589)

30 July 2017

title

A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate (English)

1 reference

epidermal growth factor receptor

30 July 2017

main subject

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Coiled-coil domain containing 88A

GOA release 2020-03-11

1 reference

maintenance of protein location in plasma membrane

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

11

Marilyn G Farquhar

1 reference

30 July 2017

Pradipta Ghosh

1

1 reference

30 July 2017

Anthony O Beas

2

1 reference

30 July 2017

Scott J Bornheimer

3

1 reference

30 July 2017

Mikel Garcia-Marcos

4

1 reference

30 July 2017

Erin P Forry

5

1 reference

30 July 2017

Carola Johannson

6

1 reference

30 July 2017

Jason Ear

7

1 reference

30 July 2017

Barbara H Jung

8

1 reference

30 July 2017

Betty Cabrera

9

1 reference

30 July 2017

John M Carethers

10

1 reference

30 July 2017

publication date

12 May 2010

1 reference

Molecular Biology of the Cell

30 July 2017

published in

1 reference

30 July 2017

volume

21

1 reference

30 July 2017

issue

13

1 reference

30 July 2017

page(s)

2338-2354

1 reference

describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2893996/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration

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Endosomes: a legitimate platform for the signaling train

5 July 2018

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GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Activation of Galphai3 triggers cell migration via regulation of GIV.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

An actin-binding protein Girdin regulates the motility of breast cancer cells

5 July 2018

1 reference

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Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.

5 July 2018

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Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.

5 July 2018

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Cell surface restriction of EGFR by a tenascin cytotactin-encoded EGF-like repeat is preferential for motility-related signaling

5 July 2018

1 reference

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Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.

5 July 2018

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Metastatic potential of 21T human breast cancer cells depends on Akt/protein kinase B activation

5 July 2018

1 reference

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Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways

5 July 2018

1 reference

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The connection between splicing and cancer.

5 July 2018

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Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation

5 July 2018

1 reference

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A biological approach to computational models of proteomic networks

5 July 2018

1 reference

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Akt/PKB regulates actin organization and cell motility via Girdin/APE

5 July 2018

1 reference

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Simulating the impact of a molecular 'decision-process' on cellular phenotype and multicellular patterns in brain tumors.

5 July 2018

1 reference

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The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction

5 July 2018

1 reference

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Newest findings on the oldest oncogene; how activated src does it

5 July 2018

1 reference

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Localization of receptor-mediated signal transduction pathways: the inside story.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Regression of Peyer's patches in G alpha i2 deficient mice prior to colitis is associated with reduced expression of Bcl-2 and increased apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Growth factor-induced cell motility in tumor invasion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Messenger-RNA-binding proteins and the messages they carry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Histone H3 phosphorylation and cell division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Synchronization of the G1/S transition in response to corneal debridement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Relationship between cell migration and cell cycle during the initiation of epithelial to fibroblastoid transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

An animal model for colon cancer metastasis: establishment and characterization of murine cell lines with enhanced liver-metastasizing ability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Tumor progression in four mammary epithelial cell lines derived from the same patient

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Proliferation versus migration in platelet-derived growth factor signaling: the key role of endocytosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Epidermal growth factor receptor-dependent PI3K-activation promotes restitution of wounded human gastric epithelial monolayers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Migration and proliferation dichotomy in tumor-cell invasion.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

Dichotomy of astrocytoma migration and proliferation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893996

The present status of cancer chemotherapy--a summary of papers delivered at the Cherry Hill Conference on "a critical evaluation of cancer chemotherapy"

29 October 2018

1 reference

12 December 2020

Cell migration and DNA synthesis in organ culture of human skin

1 reference

12 December 2020

Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase acti

1 reference

12 December 2020

Adenosine modulates cell proliferation in human colonic carcinoma. II. Differential behavior of HT29, DLD-1, Caco-2 and SW403 cell lines

1 reference

12 December 2020

Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis

1 reference

12 December 2020

Transducing the signals: a G protein takes a new identity

1 reference

12 December 2020

Molecular mechanisms of metastasis

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E10-01-0028

1 reference

30 July 2017

1 reference

30 July 2017

1 reference