(Q33954369)

30 July 2017

title

A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins (English)

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30 July 2017

main subject

Clostridium difficile

0 references

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Mark Lynch

2

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Jennifer K Dowling

Jennifer K Dowling

7

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Claire E McCoy

Claire E McCoy

6

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Sylvie Amu

Sylvie Amu

4

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Charles Oliver Morton

Charles O Morton

15

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Sinéad M. Smith

Sinead M Smith

3

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Thomas R. Rogers

Thomas R Rogers

16

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Padraic G. Fallon

Padraic G Fallon

17

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Luke A. J. O'Neill

Luke A O'Neill

18

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author name string

Anthony Ryan

1

1 reference

30 July 2017

Hendrik J Nel

5

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30 July 2017

Eve Draper

8

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30 July 2017

Vincent O'Reilly

9

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30 July 2017

Ciara McCarthy

10

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30 July 2017

Julie O'Brien

11

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30 July 2017

Déirdre Ní Eidhin

12

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30 July 2017

Mary J O'Connell

13

1 reference

30 July 2017

Brian Keogh

14

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30 July 2017

Dermot Kelleher

19

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30 July 2017

Christine E Loscher

20

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30 July 2017

publication date

30 June 2011

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

6

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30 July 2017

page(s)

e1002076

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

30 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

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Toxin B is essential for virulence of Clostridium difficile

28 July 2018

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Structural insights into the molecular organization of the S-layer from Clostridium difficile

28 July 2018

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A mouse model of Clostridium difficile-associated disease

28 July 2018

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IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection

28 July 2018

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The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses

28 July 2018

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Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

28 July 2018

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

28 July 2018

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Signalling of toll-like receptors.

28 July 2018

1 reference

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The role of toll-like receptors in macrophages.

28 July 2018

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The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

28 July 2018

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How important are Toll-like receptors for antimicrobial responses?

28 July 2018

1 reference

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Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection

28 July 2018

1 reference

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Innate control of adaptive immunity: dendritic cells and beyond

28 July 2018

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

28 July 2018

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Role of Toll-like receptors in health and diseases of gastrointestinal tract

28 July 2018

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How Toll-like receptors signal: what we know and what we don't know

28 July 2018

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TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway

28 July 2018

1 reference

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Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins

28 July 2018

1 reference

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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

28 July 2018

1 reference

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Toll-like receptor signalling

28 July 2018

1 reference

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Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology.

28 July 2018

1 reference

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Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

28 July 2018

1 reference

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The pathogenicity of Clostridium difficile.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128122

Roles of the surface layer proteins of Campylobacter fetus subsp. fetus in ovine abortion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128122

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128122

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128122

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128122

Atypical disease after Bordetella pertussis respiratory infection of mice with targeted disruptions of interferon-gamma receptor or immunoglobulin mu chain genes

28 July 2018

1 reference

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Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Active immunization of hamsters against Clostridium difficile infection using surface-layer protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Human antibody response to surface layer proteins in Clostridium difficile infection

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

CD14 is required for MyD88-independent LPS signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Infection of hamsters with epidemiologically important strains of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Production of IL-12, IL-23 and IL-27p28 by bone marrow-derived conventional dendritic cells rather than macrophages after LPS/TLR4-dependent induction by Salmonella Enteritidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Sequence and phylogenetic analysis of the gene for surface layer protein, slpA, from 14 PCR ribotypes of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002076

Characterization of surface layer proteins from different Clostridium difficile clinical isolates

21 January 2018

1 reference

12 December 2020

Cholera Toxin Promotes the Induction of Regulatory T Cells Specific for Bystander Antigens by Modulating Dendritic Cell Activation

1 reference

12 December 2020

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

1 reference

12 December 2020

Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells

1 reference

12 December 2020

Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile

1 reference

12 December 2020

Clostridium difficile comes of age

1 reference

12 December 2020

Clostridium difficile TxAC314 and SLP-36kDa enhance the immune response toward a co-administered antigen

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002076

Identifiers

DOI

1 reference

30 July 2017

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30 July 2017

1 reference