(Q33975045)

30 July 2017

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title

Genetics, chemistry, and function of the IGF/IGFBP system (English)

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30 July 2017

Collett-Solberg PF

1

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30 July 2017

Cohen P

series ordinal

2

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30 July 2017

language of work or name

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1 April 2000

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30 July 2017

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30 July 2017

12

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30 July 2017

121-136

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30 July 2017

2

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https://scigraph.springernature.com/pub.10.1385/endo:12:2:121

30 July 2017

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cites work

Insulin-like growth factor-binding protein-5 is cleaved by physiological concentrations of thrombin

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12 December 2020

An IGF binding protein is an inhibitor of fgf stimulation

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12 December 2020

7S nerve growth factor is an insulin-like growth factor-binding protein protease

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12 December 2020

Recombinant human insulin-like growth factor (IGF) binding protein-3 stimulates prostate carcinoma cell proliferation via an IGF-dependent mechanism. Role of serine proteases

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12 December 2020

Insulin-like growth factor-binding proteins: functional diversity or redundancy?

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12 December 2020

Interaction between the insulin-like growth factor family and the integrin receptor family in tissue repair processes. Evidence in a rabbit ear dermal ulcer model

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12 December 2020

Hormonal and nutritional regulation of IGF-I and its binding proteins

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12 December 2020

Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells.

1 reference

12 December 2020

Insulin-like growth factor (IGF)-I and -II and IGF-binding proteins-1, -2, and -3 in children and adolescents with diabetes mellitus: correlation with metabolic control and height attainment.

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12 December 2020

Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures

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12 December 2020

Insulin-Like Growth Factor Binding Proteins in Maternal Serum Throughout Gestation and in the Puerperium: Effects of a Pregnancy-Associated Serum Protease Activity*

1 reference

12 December 2020

Coculture of primary rat hepatocytes and nonparenchymal cells permits expression of insulin-like growth factor binding protein-3 in vitro

1 reference

12 December 2020

Nuclear localization of insulin-like growth factor binding protein 3 in a lung cancer cell line

1 reference

12 December 2020

Identification of O-glycosylation sites and partial characterization of carbohydrate structure and disulfide linkages of human insulin-like growth factor binding protein 6

1 reference

12 December 2020

Insulin-like growth factor binding protein (IGFBP)-3 protease activity secreted by MCF-7 breast cancer cells: inhibition by IGFs does not require IGF-IGFBP interaction

1 reference

12 December 2020

Effects of recombinant human insulin-like growth factor I on glomerular dynamics in the rat.

1 reference

12 December 2020

Insulin-like growth factor binding protein-1 levels in the diagnosis of hypoglycemia caused by hyperinsulinism.

1 reference

12 December 2020

Regulation of insulin-like growth factor (IGF)-binding protein-6 and mannose 6-phosphate/IGF-II receptor expression in IGF-IL-overexpressing NIH 3T3 cells

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12 December 2020

Clinical aspects of insulin-like growth factor binding proteins

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12 December 2020

Effect of glucocorticoid on insulin-like growth factor (IGF) regulation of IGF-binding protein expression in fibroblasts

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12 December 2020

An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.

1 reference

12 December 2020

Proteins in tissue extracts which bind insulin-like growth factor binding protein-3 (IGFBP-3)

1 reference

12 December 2020

Acid-activated insulin-like growth factor binding protein protease activity of cathepsin D in normal and malignant prostatic epithelial cells and seminal plasma

1 reference

12 December 2020

Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) is a potential tumor suppressor protein for prostate cancer

1 reference

12 December 2020

Structure and function of the HOX A1 human homeobox gene cDNA

1 reference

12 December 2020

Regulation of insulin-like growth factor-binding-protein-1, 2, 3, 4, 5, and 6: synthesis, secretion, and gene expression in estrogen receptor-negative human breast carcinoma cells

1 reference

12 December 2020

novH: differential expression in developing kidney and Wilm's tumors

1 reference

12 December 2020

Cellular actions of insulin-like growth factor binding proteins

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12 December 2020

Primary structure of a putative serine protease specific for IGF-binding proteins

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12 December 2020

Glucocorticoid-induced growth arrest of lung alveolar epithelial cells is associated with increased production of insulin-like growth factor binding protein-2

1 reference

12 December 2020

Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells

1 reference

12 December 2020

Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations

1 reference

12 December 2020

Expression and down-regulation by retinoic acid of IGF binding protein-2 and -4 in medium from human neuroblastoma cells.

1 reference

12 December 2020

Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats

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12 December 2020

The role of the insulin-like growth factor system in human cancer

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12 December 2020

Purification and molecular cloning of prostacyclin-stimulating factor from serum-free conditioned medium of human diploid fibroblast cells

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12 December 2020

Castration-induced apoptosis in the rat ventral prostate is associated with increased expression of genes encoding insulin-like growth factor binding proteins 2,3,4 and 5

1 reference

12 December 2020

Insulin-like growth factor-binding protein (IGF-BP) inhibition of granulosa cell function: effect on cyclic adenosine 3',5'-monophosphate, deoxyribonucleic acid synthesis, and comparison with the effect of an IGF-I antibody

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12 December 2020

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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12 December 2020

Insulin and IGF binding by IGFBP-3 fragments derived from proteolysis, baculovirus expression and normal human urine

1 reference

12 December 2020

Developmental regulation of Mac25/insulin-like growth factor-binding protein-7 expression in skeletal myogenesis

1 reference

12 December 2020

In vivo effects of insulin-like growth factor-I on the development of sensory pathways: analysis of the primary somatic sensory cortex (S1) of transgenic mice.

1 reference

12 December 2020

Structure and chromosomal localization of human insulin-like growth factor-binding protein genes.

1 reference

12 December 2020

The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins

1 reference

12 December 2020

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

1 reference

12 December 2020

Abnormal regulation of insulin-like growth factor binding proteins in adolescents with insulin-dependent diabetes.

1 reference

12 December 2020

Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells

1 reference

12 December 2020

The 16-kDa proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 inhibits the mitogenic action of fibroblast growth factor on mouse fibroblasts with a targeted disruption of the type 1 IGF receptor gene

1 reference

12 December 2020

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.

1 reference

12 December 2020

Insulin-like growth factor-binding protein-1 modulates blood glucose levels

1 reference

12 December 2020

Cell adhesion activity of a 30-kDa major secreted protein from human bladder carcinoma cells

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12 December 2020

Human insulin-like growth factor binding protein-6 is O-glycosylated

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12 December 2020

A proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 that fails to bind IGFs inhibits the mitogenic effects of IGF-I and insulin

1 reference

12 December 2020

Transfection of the human insulin-like growth factor binding protein-3 gene into Balb/c fibroblasts inhibits cellular growth

1 reference

12 December 2020

Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

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12 December 2020

IGFBP-3 and IGFBP-5 association with endothelial cells: role of C-terminal heparin binding domain

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12 December 2020

Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome

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12 December 2020

Insulin differentially alters transcapillary movement of intravascular IGFBP-1, IGFBP-2 and endothelial cell IGF-binding proteins in the rat heart

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12 December 2020

Structural and functional studies of insulin-like growth factor binding proteins in the ovary

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12 December 2020

Differential cellular synthesis of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 within human liver

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12 December 2020

Induction of the growth inhibitor IGF-binding protein 3 by p53

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12 December 2020

Co-administration of insulin-like growth factor (IGF)-I and IGF-binding protein-1 stimulates wound healing in animal models.

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12 December 2020

Regulation of endothelial IGFBP-3 synthesis and secretion by IGF-I and TGF-beta

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12 December 2020

Proteolysis of insulin-like growth factor binding protein-3 during rat pregnancy: a role for matrix metalloproteinases

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12 December 2020

Regulation and function of insulin-like growth factor-binding protein-1.

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12 December 2020

Heparin inhibition of insulin-like growth factor-binding protein-3 binding to human fibroblasts and rat glioma cells: role of heparan sulfate proteoglycans.

1 reference

12 December 2020

Proteolysis of Insulin-Like Growth Factors (IGF) and IGF Binding Proteins by Cathepsin D1

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12 December 2020

Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells

1 reference

12 December 2020

Effect of glucose on insulin-like growth factor binding protein-4 proteolysis

1 reference

12 December 2020

Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I.

1 reference

12 December 2020

Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media

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12 December 2020

Serum levels of insulin-like growth factor binding proteins (IGFBP)-4 and -5 correlate with bone mineral density in growth hormone (GH)-deficient adults and increase with GH replacement therapy.

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12 December 2020

Role of insulin-like growth factors in embryonic and postnatal growth

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12 December 2020

Infused IGF-I/IGFBP-3 complex causes glomerular localization of IGF-I in the rat kidney.

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12 December 2020

Evidence that insulin-like growth factor I increases renal plasma flow and glomerular filtration rate in fasted rats

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12 December 2020

Growth hormone and parathyroid hormone stimulate IGFBP-3 in rat osteoblasts

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12 December 2020

In vivo proteolysis of serum insulin-like growth factor (IGF) binding protein-3 results in increased availability of IGF to target cells

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12 December 2020

The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action

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12 December 2020

Cortisol increases plasma insulin-like growth factor binding protein-1 in humans

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12 December 2020

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

12 December 2020

Identification and characterization of genes differentially expressed in meningiomas

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12 December 2020

Insulin-like growth factor (IGF) I and retinoic acid induce the synthesis of IGF-binding protein 5 in rat osteoblastic cells

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12 December 2020

Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit

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12 December 2020

Physiologic and clinical relevance of the insulin-like growth factor binding proteins

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12 December 2020

Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D.

1 reference

12 December 2020

Insulin-like growth factor binding protein-3 proteolysis in children with insulin-dependent diabetes mellitus: a possible role for insulin in the regulation of IGFBP-3 protease activity

1 reference

12 December 2020

Effect of human insulin-like growth factor-binding protein-1 on the half-life and action of administered insulin-like growth factor-I in rats

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12 December 2020

Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily.

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12 December 2020

Insulin-like growth factor-binding protein-2 concentrations in cerebrospinal fluid and serum of children with malignant solid tumors or acute leukemia

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12 December 2020

Interleukin-1 and tumor necrosis factor-alpha increase insulin-like growth factor-binding protein-3 (IGFBP-3) production and IGFBP-3 protease activity in human articular chondrocytes.

1 reference

12 December 2020

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition

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12 December 2020

A factor contained in plasma is required for IGF binding protein-1 to potentiate the effect of IGF-I on smooth muscle cell DNA synthesis

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12 December 2020

IL-6 stimulation of insulin-like growth factor binding protein (IGFBP)-1 production.

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12 December 2020

Insulin-Like Growth Factor (IGF)-Binding Protein-3 Blocks IGF-I-Induced Receptor Down-Regulation and Cell Desensitization in Cultured Bovine Fibroblasts*

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12 December 2020

Evidence that human bone cells in culture secrete insulin-like growth factor (IGF)-II and IGF binding protein-3 but not acid-labile subunit both under basal and regulated conditions

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12 December 2020

Organization, expression, and chromosomal location of the mouse insulin-like growth factor binding protein 5 gene

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12 December 2020

Insulin-like growth factor binding protein-3 is functionally altered in pregnancy plasma.

1 reference

12 December 2020

Recombinant human insulin-like growth factor binding proteins 4, 5, and 6: biological and physiochemical characterization

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12 December 2020

Prostaglandin E2 up-regulates insulin-like growth factor binding protein-3 expression and synthesis in human articular chondrocytes by a c-AMP-independent pathway: role of calcium and protein kinase A and C

1 reference

12 December 2020

Insulin-like growth factors stimulate the release of insulin-like growth factor-binding protein-3 (IGFBP-3) and degradation of IGFBP-4 in nonsmall cell lung cancer cell lines

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12 December 2020

Expression of human insulin-like growth factor-binding protein-3 in transgenic mice.

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12 December 2020

The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans

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12 December 2020

Phosphorylation of insulin-like growth factor binding proteins

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12 December 2020

Regulation of the insulin-like growth factor system by acute acidosis

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12 December 2020

Acid-labile subunit of human insulin-like growth factor-binding protein complex: measurement, molecular, and clinical evaluation

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12 December 2020

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

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12 December 2020

Insulin-like growth factors and their binding proteins: biological actions

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12 December 2020

Gene expression of insulin-like growth factors (IGFs), the type 1 IGF receptor, and IGF-binding proteins in dexamethasone-induced fetal growth retardation

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12 December 2020

Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids.

1 reference

12 December 2020

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

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12 December 2020

Episomal expression of sense and antisense insulin-like growth factor (IGF)-binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I.

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12 December 2020

Long-term treatment of Laron type dwarfs with insulin-like growth factor-1 increases serum insulin-like growth factor-binding protein-3 in the absence of growth hormone activity

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12 December 2020

Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas

1 reference

12 December 2020

Insulin-like growth factor-binding protein-6 levels are elevated in serum of children with chronic renal failure: a report of the Southwest Pediatric Nephrology Study Group

1 reference

12 December 2020

Insulin-like growth factor binding proteins in the human circulation: a review.

1 reference

12 December 2020

Multihormonal regulation of insulin-like growth factor-binding protein-1 in rat H4IIE hepatoma cells: the dominant role of insulin

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12 December 2020

Insulin-like growth factor binding protein (IGFBP) proteases: functional regulators of cell growth

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12 December 2020

Increased levels of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 are associated with malignancy in sporadic adrenocortical tumors

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12 December 2020

New perspectives in cell adhesion: RGD and integrins

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12 December 2020

Molecular forms of serum insulin-like growth factor (IGF)-binding proteins in man: relationships with growth hormone and IGFs and physiological significance

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12 December 2020

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12 December 2020

Differential regulation by TGF-beta 1 and insulin of insulin-like growth factor binding protein-2 in IEC-6 cells

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12 December 2020

Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts

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12 December 2020

The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene

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12 December 2020

Insulin-like growth factor-binding protein-1 inhibits binding of IGF-I on fetal skin fibroblasts but stimulates their DNA synthesis

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12 December 2020

Insulin-like growth factor binding proteins and their regulation.

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12 December 2020

Dual regulation of insulin-like growth factor binding protein-1 levels by insulin and cortisol during fasting.

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12 December 2020

Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3): effects on the glycemic and growth promoting activities of rhIGF-1 in the rat.

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12 December 2020

Production of insulin-like growth factors and their binding proteins in primary cultures of rat liver parenchymal and nonparenchymal cells

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12 December 2020

Localization of insulin-like growth factor genes to human chromosomes 11 and 12

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12 December 2020

Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.

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12 December 2020

The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

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12 December 2020

Intranuclear localization of insulin-like growth factor binding protein-3 (IGFBP-3) during cell division in human keratinocytes

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12 December 2020

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

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12 December 2020

The role of IGFBP-3 in the regulation of IGFBP-4 proteolysis

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12 December 2020

Insulin-like growth factor binding proteins: a review of methodological aspects of their purification, analysis and regulation

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12 December 2020

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene

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12 December 2020

Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid

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12 December 2020

Retinoic acid regulates insulin-like growth factor-binding protein expression in human osteoblast cells

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12 December 2020

Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics

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12 December 2020

Insulin-Like Growth Factor Binding Proteins: Structural and Molecular Relationships

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12 December 2020

Phenotypic manifestations of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 overexpression in transgenic mice

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12 December 2020

Endogenous cathepsin D-mediated hydrolysis of insulin-like growth factor-binding proteins in cultured human prostatic carcinoma cells

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12 December 2020

Tumor necrosis factor alpha stimulates insulin-like growth factor binding protein 3 expression in cultured porcine Sertoli cells

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12 December 2020

Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma

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12 December 2020

Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis

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12 December 2020

Proteolytic activity is involved in changes in intrafollicular insulin-like growth factor-binding protein levels during growth and atresia of ovine ovarian follicles

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12 December 2020

Cellular localization and regulation of gene expression for components of the insulin-like growth factor ternary binding protein complex

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12 December 2020

Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.

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12 December 2020

Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts

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12 December 2020

Insulin-like growth factor-I (IGF-I) regulates IGF-binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells

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12 December 2020

Growth stimulation by transfection of intestinal epithelial cells with an antisense insulin-like growth factor binding protein-2 construct

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12 December 2020

Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts

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12 December 2020

Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients

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12 December 2020

Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs) -3, -5, and -6 inhibit IGFBP-4 degradation

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12 December 2020

Radioimmunoassay of insulin-like growth factor-binding protein-6 in human serum and other body fluids

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12 December 2020

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

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12 December 2020

Evidence for insulin-like growth factor (IGF)-independent transcriptional regulation of IGF binding protein-3 by growth hormone in SKHEP-1 human hepatocarcinoma cells

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12 December 2020

Physical mapping of human loci homologous to the chicken nov proto-oncogene

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12 December 2020

Effects of caloric or protein restriction on insulin-like growth factor-I (IGF-I) and IGF-binding proteins in children and adults.

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12 December 2020

Identifiers

DOI

10.1385/ENDO:12:2:121

1 reference

Dimensions Publication ID

30 July 2017

0 references

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