(Q33979793)

30 July 2017

The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy (English)

1 reference

30 July 2017

Emilia Favuzzi

4

0 references

Daniela Annibali

object named as

Daniela Annibali

2

0 references

Laura Soucek

object named as

Laura Soucek

7

0 references

author name string

Mauro Savino

1

1 reference

30 July 2017

Nicoletta Carucci

3

1 reference

30 July 2017

Michael D Cole

5

1 reference

30 July 2017

Gerard I Evan

6

1 reference

30 July 2017

Sergio Nasi

8

1 reference

30 July 2017

language of work or name

English

0 references

publication date

21 July 2011

1 reference

30 July 2017

1 reference

30 July 2017

6

1 reference

30 July 2017

7

1 reference

30 July 2017

e22284

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

start time

21 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3141027/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Endogenous Myc maintains the tumor microenvironment

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5 July 2018

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In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc/Max dimerization

5 July 2018

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Myc proteins as therapeutic targets

5 July 2018

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Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc

5 July 2018

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5 July 2018

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A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

5 July 2018

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5 July 2018

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HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.

5 July 2018

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Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells

5 July 2018

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Distinct thresholds govern Myc's biological output in vivo

5 July 2018

1 reference

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N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor

5 July 2018

1 reference

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Reflecting on 25 years with MYC.

5 July 2018

1 reference

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Analysis of Myc-induced histone modifications on target chromatin

5 July 2018

1 reference

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Modelling Myc inhibition as a cancer therapy

5 July 2018

1 reference

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An extended transcriptional network for pluripotency of embryonic stem cells

5 July 2018

1 reference

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HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

5 July 2018

1 reference

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Myc goes global: new tricks for an old oncogene.

5 July 2018

1 reference

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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function

5 July 2018

1 reference

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Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc

5 July 2018

1 reference

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Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene

5 July 2018

1 reference

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Myc influences global chromatin structure.

5 July 2018

1 reference

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Transcriptional activation by the Myc oncoprotein.

5 July 2018

1 reference

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Targeting of Miz-1 is essential for Myc-mediated apoptosis

5 July 2018

1 reference

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Cancer therapeutics: targeting the dark side of Myc.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

A microRNA polycistron as a potential human oncogene

5 July 2018

1 reference

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C-Myc-independent restoration of multiple phenotypes by two C-Myc target genes with overlapping functions

5 July 2018

1 reference

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Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Omomyc expression in skin prevents Myc-induced papillomatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

5 July 2018

1 reference

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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

5 July 2018

1 reference

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Low molecular weight inhibitors of Myc-Max interaction and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Transcriptional repression by Myc.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

A large scale genetic analysis of c-Myc-regulated gene expression patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Negative regulation of the mammalian UV response by Myc through association with Miz-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Repression of p15INK4b expression by Myc through association with Miz-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

c-Myc enhances protein synthesis and cell size during B lymphocyte development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

c-Myc target genes involved in cell growth, apoptosis, and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Design and properties of a Myc derivative that efficiently homodimerizes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Commonly occurring loss and mutation of the MXI1 gene in prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

An alternative pathway for gene regulation by Myc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Production of high-titer helper-free retroviruses by transient transfection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

The MYC protein activates transcription of the alpha-prothymosin gene.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141027

The interplay between MYC and HIF in cancer.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022284

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0022284

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

21 January 2018

1 reference

12 December 2020

Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation

1 reference

12 December 2020

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

1 reference

12 December 2020

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0022284

Identifiers

DOI

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference