(Q33979830)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

1

1 reference

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5 February 2020

Pietro Luigi Poliani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Francesca Schena

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Christian E Busse

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Fabio Facchetti

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Fabio Grassi

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Anna Villa

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

11

Alberto Martini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

13

Mirjam van der Burg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Veronica Marrella

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Aisha V Sauer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Maria Ravanini

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Dario Strina

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Stephan Regenass

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Hedda Wardemann

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Antonius G Rolink

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Paolo Vezzoni

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Elisabetta Traggiai

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

14 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

5 February 2020

published in

1 reference

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5 February 2020

volume

207

1 reference

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5 February 2020

issue

7

1 reference

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5 February 2020

page(s)

1525-1540

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency

5 February 2020

cites work

1 reference

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Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Bcl6 mediates the development of T follicular helper cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Antiviral immune responses: triggers of or triggered by autoimmunity?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

AIRE regulates T-cell-independent B-cell responses through BAFF.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Omenn syndrome: inflammation in leaky severe combined immunodeficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Regulation and functions of Blimp-1 in T and B lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

RAG-dependent primary immunodeficiencies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

The role of the BAFF/APRIL system on T cell function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Follicular B helper T cells in antibody responses and autoimmunity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Expression and reexpression of recombination activating genes: relevance to the development of autoimmune states

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

BAFF AND APRIL: a tutorial on B cell survival

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Plasma cell differentiation requires the transcription factor XBP-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Omenn syndrome: a disorder of Rag1 and Rag2 genes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Partial V(D)J recombination activity leads to Omenn syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

CpG motifs in bacterial DNA trigger direct B-cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

5 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Homeostatic and functional analysis of mature B cells in lambda5-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Interleukin-21 stimulates B-cell immunoglobulin E synthesis in human beings concomitantly with activation-induced cytidine deaminase expression and differentiation into plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Familial Reticuloendotheliosis with Eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Cloning and expression of murine Ig genes from single B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Cellular niches controlling B lymphocyte behavior within bone marrow during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Induction of TNBS colitis in mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901059

Defect of regulatory T cells in patients with Omenn syndrome

29 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Control of B-cell responses by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091928

Censoring of autoreactive B cell development by the pre-B cell receptor

21 January 2018

1 reference

12 December 2020

Intrathymic restriction and peripheral expansion of the T-cell repertoire in Omenn syndrome

1 reference

12 December 2020

Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin

1 reference

12 December 2020

Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses

1 reference

12 December 2020

Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus

1 reference

12 December 2020

Combined immunodeficiency and reticuloendotheliosis with eosinophilia

1 reference

12 December 2020

Oligoclonal expansion of CD45RO+ T lymphocytes in Omenn syndrome

1 reference

12 December 2020

Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091928

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547828%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

20547828

1 reference