(Q33980991)

30 July 2017

title

Mechanisms and frequency of resistance to premafloxacin in Staphylococcus aureus: novel mutations suggest novel drug-target interactions (English)

1 reference

30 July 2017

main subject

Staphylococcus aureus

1 reference

D Ince

1

1 reference

30 July 2017

D C Hooper

series ordinal

2

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

Antimicrobial Agents and Chemotherapy

30 July 2017

published in

1 reference

30 July 2017

volume

44

1 reference

30 July 2017

issue

12

1 reference

30 July 2017

page(s)

3344-3350

1 reference

Gatifloxacin activity against quinolone-resistant gyrase: allele-specific enhancement of bacteriostatic and bactericidal activities by the C-8-methoxy group

30 July 2017

cites work

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28 July 2018

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28 July 2018

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ParC and GyrA may be interchangeable initial targets of some fluoroquinolones in Streptococcus pneumoniae

28 July 2018

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DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae.

28 July 2018

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Effects of mutations in GrlA of topoisomerase IV from Staphylococcus aureus on quinolone and coumarin activity

28 July 2018

1 reference

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Identification of active site residues in the "GyrA" half of yeast DNA topoisomerase II.

28 July 2018

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28 July 2018

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Mutations in topoisomerase IV and DNA gyrase of Staphylococcus aureus: novel pleiotropic effects on quinolone and coumarin activity

28 July 2018

1 reference

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DNA gyrase, topoisomerase IV, and the 4-quinolones

28 July 2018

1 reference

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Crystal structure of the breakage-reunion domain of DNA gyrase

28 July 2018

1 reference

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In vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary importance.

28 July 2018

1 reference

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Increased expression of fibronectin-binding proteins by fluoroquinolone-resistant Staphylococcus aureus exposed to subinhibitory levels of ciprofloxacin.

28 July 2018

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Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.

28 July 2018

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Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV.

28 July 2018

1 reference

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Quinolone resistance mutations in topoisomerase IV: relationship to the flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase is the secondary target of fluoroquinolones in Staphylococcus aureus.

28 July 2018

1 reference

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Alterations in the DNA topoisomerase IV grlA gene responsible for quinolone resistance in Staphylococcus aureus.

28 July 2018

1 reference

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Inducible NorA-mediated multidrug resistance in Staphylococcus aureus

28 July 2018

1 reference

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A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90203

Structure-activity and structure-side-effect relationships for the quinolone antibacterials

28 July 2018

1 reference

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Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus

28 July 2018

1 reference

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Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus

28 July 2018

1 reference

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Confirmation of protoplast fusion-derived linkages in Staphylococcus aureus by transformation with protoplast DNA.

28 July 2018

1 reference

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Transformation of Chromosomal and Plasmid Characters in Staphylococcus aureus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90203

A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus

28 July 2018

1 reference

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Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus

28 July 2018

1 reference

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A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP.

29 October 2018

1 reference

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Bacterial topoisomerases, anti-topoisomerases, and anti-topoisomerase resistance.

29 October 2018

1 reference

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Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome

29 October 2018

1 reference

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Mechanistic studies of amsacrine-resistant derivatives of DNA topoisomerase II. Implications in resistance to multiple antitumor drugs targeting the enzyme.

29 October 2018

1 reference

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The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90203

A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11083638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Premafloxacin: a projected veterinary use fluoro-quinolone with significant activity against multi-resistant gram-positive human pathogens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11083638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanisms of fluoroquinolone resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11083638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.44.12.3344-3350.2000

1 reference

30 July 2017

1 reference

30 July 2017

1 reference