(Q73538438)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons (English)

1 reference

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4 November 2019

3

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4 November 2019

author name string

J Dong

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

J Walker

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 March 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 November 2019

published in

1 reference

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4 November 2019

volume

275

1 reference

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4 November 2019

issue

11

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4 November 2019

page(s)

7980-7987

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Antitopoisomerase drug action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Using yeast to understand drugs that target topoisomerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Fluoroquinolone antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

New topoisomerase essential for chromosome segregation in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Analysis of the NH2-terminal 83rd amino acid of Escherichia coli GyrA in quinolone-resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

High-level fluoroquinolone resistance in a Salmonella typhimurium isolate due to alterations in both gyrA and gyrB genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

A mutant yeast topoisomerase II (top2G437S) with differential sensitivity to anticancer drugs in the presence and absence of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Structure and mechanism of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Identification of active site residues in the "GyrA" half of yeast DNA topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Increased drug affinity as the mechanistic basis for drug hypersensitivity of a mutant type II topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7980

21 January 2018

Identifiers

DOI

10.1074/JBC.275.11.7980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10713116%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference