(Q33981695)

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A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

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30 July 2017

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach (English)

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PubMed publication ID

30 July 2017

atherosclerosis

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inferred from title

Braxton D. Mitchell

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30 July 2017

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30 July 2017

Terho Lehtimäki

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Terho Lehtimäki

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Matthew Traylor

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Matthew Traylor

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30 July 2017

Kari-Matti Mäkelä

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Kari-Matti Mäkelä

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Laura L. Kilarski

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Laura L Kilarski

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Wei Zhao

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Giorgio B Boncoraglio

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Giorgio B Boncoraglio

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Robin Lemmens

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Vincent N Thijs

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Vincent Thijs

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Steve Bevan

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Cathie Sudlow

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Christopher Levi

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Christopher Levi

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Danish Saleheen

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Danish Saleheen

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Agnieszka Słowik

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Agnieszka Slowik

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Martin Dichgans

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Martin Dichgans

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Jonathan Rosand

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Jonathan Rosand

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Rainer Malik

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Peter M. Rothwell

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Peter M Rothwell

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James F Meschia

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James F Meschia

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Ale Algra

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Joshua C Bis

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Steven J Kittner

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Kerri L Wiggins

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Kerri L Wiggins

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Hugh S Markus

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Mike A Nalls

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Elizabeth Holliday

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Elizabeth G Holliday

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Sefanja Achterberg

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Sefanja Achterberg

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Paul I W de Bakker

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Paul I W de Bakker

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John R Attia

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William J Devan

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Yu-Ching Cheng

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Emma Raitoharju

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30 July 2017

METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2)

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30 July 2017

Niku Oksala

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Arne Lindgren

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Jane M Maguire

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Matthew Walters

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30 July 2017

Pankaj Sharma

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30 July 2017

publication date

31 July 2014

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30 July 2017

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30 July 2017

10

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30 July 2017

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30 July 2017

e1004469

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30 July 2017

copyright license

Creative Commons CC0 License

31 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

1 reference

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5 July 2018

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5 July 2018

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

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Informed conditioning on clinical covariates increases power in case-control association studies

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5 July 2018

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5 July 2018

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

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5 July 2018

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5 July 2018

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

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5 July 2018

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

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5 July 2018

Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study

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5 July 2018

Genome-wide association analysis of ischemic stroke in young adults

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5 July 2018

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

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5 July 2018

Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies

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5 July 2018

Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data

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5 July 2018

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

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5 July 2018

METAL: fast and efficient meta-analysis of genomewide association scans

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5 July 2018

Genotype imputation for genome-wide association studies

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5 July 2018

Parental occurrence of stroke and risk of stroke in their children: the Framingham study

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5 July 2018

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

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5 July 2018

Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke

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Diversity and complexity in DNA recognition by transcription factors

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Lifetime risk of stroke and dementia: current concepts, and estimates from the Framingham Study

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JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update

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Principal components analysis corrects for stratification in genome-wide association studies

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5 July 2018

The lifetime risk of stroke: estimates from the Framingham Study

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Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study).

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Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries

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Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies

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Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis.

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Genomic control for association studies

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Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

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Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice

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Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment

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Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

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Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics

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Genomics of Foam Cells and Nonfoamy Macrophages From Rabbits Identifies Arginase-I as a Differential Regulator of Nitric Oxide Production

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Identifiers

10.1371/JOURNAL.PGEN.1004469

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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