(Q33982295)

30 July 2017

title

Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation (English)

1 reference

30 July 2017

1 reference

Kathrin Theil

4

0 references

Grant S Stewart

object named as

Grant S Stewart

6

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Andrew S Turnell

11

object named as

Andrew S Turnell

1 reference

30 July 2017

9

Thomas Dobner

1 reference

30 July 2017

Andrew N Blackford

1

1 reference

30 July 2017

Rakesh N Patel

2

1 reference

30 July 2017

Natalie A Forrester

3

1 reference

30 July 2017

Peter Groitl

5

1 reference

30 July 2017

A Malcolm R Taylor

7

1 reference

30 July 2017

Iain M Morgan

8

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30 July 2017

Roger J A Grand

10

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30 July 2017

language of work or name

English

0 references

publication date

21 June 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

107

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30 July 2017

issue

27

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30 July 2017

page(s)

12251-12256

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The DNA-damage response in human biology and disease

30 July 2017

cites work

1 reference

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Regulation of protein synthesis by ionizing radiation.

5 July 2018

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Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex

5 July 2018

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Viral manipulation of DNA repair and cell cycle checkpoints

5 July 2018

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Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation

5 July 2018

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Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

ATR: an essential regulator of genome integrity

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation

5 July 2018

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A role for E1B-AP5 in ATR signaling pathways during adenovirus infection

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

TopBP1 activates the ATR-ATRIP complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins

5 July 2018

1 reference

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An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent deltaE1-E2-E3-E4 Ad5 vectors

5 July 2018

1 reference

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Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication

5 July 2018

1 reference

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Function and regulation of cullin-RING ubiquitin ligases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

The Mre11 complex is required for ATM activation and the G2/M checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

ATR and ATRIP: partners in checkpoint signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Enhanced expression of p53 in human cells infected with mutant adenoviruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

Host range mutants of adenovirus type 12 E1 defective for lytic infection, transformation, and oncogenicity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901489

A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0914605107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0914605107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference