(Q33983441)

30 July 2017

title

Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens (English)

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30 July 2017

main subject

whole genome sequencing

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6

Beth Levine

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30 July 2017

Rui Zhong

1

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30 July 2017

Jimi Kim

2

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30 July 2017

Hyun Seok Kim

3

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30 July 2017

Minsoo Kim

4

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30 July 2017

Lawrence Lum

5

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30 July 2017

Guanghua Xiao

7

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30 July 2017

Michael A White

8

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30 July 2017

Yang Xie

9

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30 July 2017

language of work or name

English

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publication date

27 June 2014

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30 July 2017

published in

Nucleic Acids Research

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30 July 2017

volume

42

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30 July 2017

issue

13

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30 July 2017

page(s)

8214-8222

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Creative Commons Attribution 3.0 Unported

30 July 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

siMacro: A Fast and Easy Data Processing Tool for Cell-Based Genomewide siRNA Screens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

Host modulators of H1N1 cytopathogenicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

siRNA off-target effects in genome-wide screens identify signaling pathway members

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

Common seed analysis to identify off-target effects in siRNA screens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

Image-based genome-wide siRNA screen identifies selective autophagy factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

MicroRNAs: target recognition and regulatory functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4117740

5 July 2018

Identifiers

DOI

10.1093/NAR/GKU306

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30 July 2017

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30 July 2017

1 reference