(Q33986335)

30 July 2017

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts (English)

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30 July 2017

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Agarwal ML

1

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30 July 2017

Agarwal A

series ordinal

2

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30 July 2017

Taylor WR

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3

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30 July 2017

Stark GR

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4

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30 July 2017

language of work or name

English

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publication date

1 August 1995

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30 July 2017

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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30 July 2017

92

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30 July 2017

8493-8497

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30 July 2017

18

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describes a project that uses

30 July 2017

MDAH041

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TR9-7

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cites work

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

p21 is a universal inhibitor of cyclin kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Sequence-specific transcriptional activation is essential for growth suppression by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Induction of WAF1/CIP1 by a p53-independent pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Cell cycle regulation of gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Evidence for a second cell cycle block at G2/M by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

A reversible arrest point in the late G1 phase of the mammalian cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Universal control mechanism regulating onset of M-phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Participation of p53 protein in the cellular response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

p53 mutations in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Cancer. p53, guardian of the genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41183

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

5 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7667317

12 December 2020

inferred from PubMed ID database lookup

Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7667317

12 December 2020

inferred from PubMed ID database lookup

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7667317

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.92.18.8493

1 reference

release_hwgnivkaujgajb6l4ygch7elga

30 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hwgnivkaujgajb6l4ygch7elga

24 November 2022

mapped directly with Wikidata item

PMCID

41183

1 reference

30 July 2017

1 reference