(Q33991071)

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Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells (English)

1 reference

Europe PubMed Central

30 July 2017

author name string

Rohan K Humphrey

1

1 reference

Europe PubMed Central

30 July 2017

Christina J Newcomb

2

1 reference

Europe PubMed Central

30 July 2017

Shu-Mei A Yu

3

1 reference

Europe PubMed Central

30 July 2017

Ergeng Hao

4

1 reference

Europe PubMed Central

30 July 2017

Doris Yu

5

1 reference

Europe PubMed Central

30 July 2017

Stan Krajewski

6

1 reference

Europe PubMed Central

30 July 2017

Keyong Du

7

1 reference

Europe PubMed Central

30 July 2017

Ulupi S Jhala

8

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

26 April 2010

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Europe PubMed Central

30 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

30 July 2017

285

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Europe PubMed Central

30 July 2017

29

1 reference

Europe PubMed Central

30 July 2017

22426-22436

1 reference

Europe PubMed Central

30 July 2017

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells

1 reference

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1 reference

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1 reference

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Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6.

1 reference

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Mitochondria mediated cell death in diabetes

1 reference

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1 reference

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JNK signaling in apoptosis

1 reference

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TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis

1 reference

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1 reference

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PKB and the mitochondria: AKTing on apoptosis

1 reference

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Mitochondrial membrane permeabilization in cell death

1 reference

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1 reference

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

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Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.

1 reference

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Apoptotic signaling pathways: caspases and stress-activated protein kinases

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A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.

1 reference

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Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades

1 reference

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TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

1 reference

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The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region

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MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

1 reference

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Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

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TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

1 reference

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Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.

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Identifiers

10.1074/JBC.M110.123786

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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