(Q33991658)

English

Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C.

scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C. (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

mitomycin C metabolic process

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

mitomycin C catabolic process

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

mitomycin C biosynthetic process

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

author name string

Y Mao

1

1 reference

Europe PubMed Central

30 July 2017

M Varoglu

2

1 reference

Europe PubMed Central

30 July 2017

D H Sherman

3

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

1 April 1999

1 reference

Europe PubMed Central

30 July 2017

Journal of Bacteriology

1 reference

Europe PubMed Central

30 July 2017

181

1 reference

Europe PubMed Central

30 July 2017

7

1 reference

Europe PubMed Central

30 July 2017

2199-2208

1 reference

Europe PubMed Central

30 July 2017

Mitomycin, a new antibiotic from Streptomyces. I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Genetic Contributions to Understanding Polyketide Synthases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Two glycosyltransferase genes, lgtF and rfaK, constitute the lipooligosaccharide ice (inner core extension) biosynthesis operon of Neisseria meningitidis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Molecular genetic methods for improving secondary-metabolite production in actinomycetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Linkage of genes essential for synthesis of a polysaccharide capsule in Sphingomonas strain S88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Identification and analysis of the Rhizobium meliloti exoAMONP genes involved in exopolysaccharide biosynthesis and mapping of promoters located on the exoHKLAMONP fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Physiology and genetics of antibiotic production and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Pathway engineering in secondary metabolite-producing actinomycetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

A general approach for identifying and cloning peptide synthetase genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Mitomycin C: a prototype bioreductive agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

The thiostrepton-resistance-encoding gene in Streptomyces laurentii is located within a cluster of ribosomal protein operons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

A comprehensive set of sequence analysis programs for the VAX

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Cloning and expression of a puromycin N-acetyl transferase gene from Streptomyces alboniger in Streptomyces lividans and Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Cloning and heterologous expression of a gene cluster for the biosynthesis of tetracenomycin C, the anthracycline antitumor antibiotic of Streptomyces glaucescens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Molecular cloning of resistance genes and architecture of a linked gene cluster involved in biosynthesis of oxytetracycline by Streptomyces rimosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Intergeneric conjugation between Escherichia coli and Streptomyces species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Basic local alignment search tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Cloning of genes involved in erythromycin biosynthesis from Saccharopolyspora erythraea using a novel actinomycete-Escherichia coli cosmid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Modular organization of genes required for complex polyketide biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

A versatile shuttle cosmid vector for use in Escherichia coli and actinomycetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Clusters of genes for the biosynthesis of antibiotics: regulatory genes and overproduction of pharmaceuticals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Genetic regulation of secondary metabolic pathways in Streptomyces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

Utilization of the intact carbamoyl group of L-(NH2CO-13C, 15N) citrulline in mitomycin biosynthesis by Streptomyces verticillatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

5 July 2018

MITOMYCINS AND PORFIROMYCIN: CHEMICAL MECHANISM OF ACTIVATION AND CROSS-LINKING OF DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

29 October 2018

3-Amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93634

29 October 2018

Biosynthetic origin of aminobenzenoid nucleus (C7N-unit) of ansamitocin, a group of novel maytansinoid antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Amino-5-hydroxybenzoic acid in antibiotic biosynthesis. VI. Directed biosynthesis studies with ansamycin antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic approach to the biosynthesis of the rifamycin-chromophore in Nocardia mediterranei. IV. Identification of 3-amino-5-hydroxybenzoic acid as a direct precursor of the seven-carbon amino starter-unit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis of shikimate metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-glucosamine and L-citrulline, precursors in mitomycin biosynthesis by Streptomyces verticillatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The identification of 3-amino-5-hydroxybenzoic acid as a new natural aromatic amino acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the streptovaricins: 3-amino-5-hydroxybenzoic acid as a precursor to the meta-C7N unit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the Biosynthesis of Mitomycin C by Streptomyces verticillatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent Advances in the Usage of Mitomycin. Proceedings of a symposium. Hawaii, March 21-24, 1991

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the ansamycin antibiotic ansatrienin (mycotrienin) by Streptomyces collinus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10094699

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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