(Q33996614)

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B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies

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scholarly article

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Europe PubMed Central

30 July 2017

B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies (English)

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Europe PubMed Central

30 July 2017

Cytomegalovirus

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Sonja Pötzsch

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Heinrich Sticht

object named as

Heinrich Sticht

6

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Thomas Stamminger

10

object named as

Thomas Stamminger

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Europe PubMed Central

30 July 2017

author name string

Nadja Spindler

2

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Europe PubMed Central

30 July 2017

Anna-Katharina Wiegers

3

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Europe PubMed Central

30 July 2017

Tanja Fisch

4

1 reference

Europe PubMed Central

30 July 2017

Pia Rücker

5

1 reference

Europe PubMed Central

30 July 2017

Nina Grieb

7

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Europe PubMed Central

30 July 2017

Tina Baroti

8

1 reference

Europe PubMed Central

30 July 2017

Florian Weisel

9

1 reference

Europe PubMed Central

30 July 2017

Luis Martin-Parras

11

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Europe PubMed Central

30 July 2017

Michael Mach

12

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Europe PubMed Central

30 July 2017

Thomas H Winkler

13

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Europe PubMed Central

30 July 2017

publication date

11 August 2011

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Europe PubMed Central

30 July 2017

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Europe PubMed Central

30 July 2017

7

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Europe PubMed Central

30 July 2017

8

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Europe PubMed Central

30 July 2017

e1002172

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Europe PubMed Central

30 July 2017

copyright license

Creative Commons Attribution 4.0 International

11 August 2011

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April 2022 Public Data File from Crossref

copyright status

0 references

Cascade of events governing cell-cell fusion induced by herpes simplex virus glycoproteins gD, gH/gL, and gB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Vaccination with murid herpesvirus-4 glycoprotein B reduces viral lytic replication but does not induce detectable virion neutralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Optimal replication of human cytomegalovirus correlates with endocytosis of glycoprotein gpUL132.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Bimolecular complementation defines functional regions of Herpes simplex virus gB that are involved with gH/gL as a necessary step leading to cell fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Clonal dissection of the human memory B-cell repertoire following infection and vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

How we treat cytomegalovirus in hematopoietic cell transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Vaccine prevention of maternal cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Passive immunization reduces murine cytomegalovirus-induced brain pathology in newborn mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Cytomegalovirus cell tropism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Comparative protein structure modeling using Modeller

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Antigenic and mutational analyses of herpes simplex virus glycoprotein B reveal four functional regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Crystal structure of glycoprotein B from herpes simplex virus 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Human cytomegalovirus infection elicits a glycoprotein M (gM)/gN-specific virus-neutralizing antibody response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Coiled-coil domains in glycoproteins B and H are involved in human cytomegalovirus membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Maternal immunity and prevention of congenital cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Antibodies, viruses and vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Disulfide bond configuration of human cytomegalovirus glycoprotein B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

The antiviral activity of antibodies in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Complex formation by human cytomegalovirus glycoproteins M (gpUL100) and N (gpUL73).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Report on a long-term study of maternal and congenital cytomegalovirus infection in Sweden. Review of prospective studies available in the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Structural domains involved in human cytomegalovirus glycoprotein B-mediated cell-cell fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Glycoprotein H of human cytomegalovirus is a major antigen for the neutralizing humoral immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Main-chain bond lengths and bond angles in protein structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Symptomatic cytomegalovirus infection in seropositive kidney recipients: reinfection with donor virus rather than reactivation of recipient virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Identification of a neutralizing epitope on glycoprotein gp58 of human cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Analysis of Interstrain Variation in Cytomegalovirus Glycoprotein B Sequences Encoding Neutralization-Related Epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Distribution of linear antigenic sites on glycoprotein gp55 of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

The gp116 of the gp58/116 complex of human cytomegalovirus represents the amino-terminal part of the precursor molecule and contains a neutralizing epitope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Characterization of a major antigenic region on gp55 of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Human Monoclonal Antibodies Neutralizing Cytomegalovirus (CMV) for Prophylaxis of CMV Disease: Report of a Phase I Trial in Bone Marrow Transplant Recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Glycoprotein gp116 of human cytomegalovirus contains epitopes for strain-common and strain-specific antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

A continuous sequence of more than 70 amino acids is essential for antibody binding to the dominant antigenic site of glycoprotein gp58 of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Antibodies to Recombinant-Derived Glycoprotein B after Natural Human Cytomegalovirus Infection Correlate with Neutralizing Activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

5 July 2018

Passive Immunization during Pregnancy for Congenital Cytomegalovirus Infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Regression of fetal cerebral abnormalities by primary cytomegalovirus infection following hyperimmunoglobulin therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Preconception vaccination with a glycoprotein B (gB) DNA vaccine protects against cytomegalovirus (CMV) transmission in the guinea pig model of congenital CMV infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

A canarypox vector expressing cytomegalovirus (CMV) glycoprotein B primes for antibody responses to a live attenuated CMV vaccine (Towne).

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Antigenic domain 1 of human cytomegalovirus glycoprotein B induces a multitude of different antibodies which, when combined, results in incomplete virus neutralization

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Recognition of human cytomegalovirus by human primary immunoglobulins identifies an innate foundation to an adaptive immune response.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Glycoprotein N subtypes of human cytomegalovirus induce a strain-specific antibody response during natural infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002172

21 January 2018

Epidemiological impact and disease burden of congenital cytomegalovirus infection in Europe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

29 October 2018

Longitudinal investigation of hearing disorders in children with congenital cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

29 October 2018

Humoral immune response to functional regions of human cytomegalovirus glycoprotein B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154849

29 October 2018

Neutralizing mechanisms of two human monoclonal antibodies against human cytomegalovirus glycoprotein 130/55

1 reference

https://pubmed.ncbi.nlm.nih.gov/21852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The humoral immune response against human cytomegalovirus is characterized by a delayed synthesis of glycoprotein-specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the outcome of renal transplantation with antibody response to cytomegalovirus strain-specific glycoprotein H epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1002172

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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