(Q33997655)

30 July 2017

title

Brain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson's disease (English)

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30 July 2017

1 reference

Christopher A Bates

1

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30 July 2017

Wei Zheng

series ordinal

2

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30 July 2017

publication date

31 July 2014

1 reference

Fluids and Barriers of the CNS

30 July 2017

published in

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30 July 2017

volume

11

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30 July 2017

page(s)

17

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Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system

30 July 2017

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28 July 2018

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Increased neuronal α-synuclein pathology associates with its accumulation in oligodendrocytes in mice modeling α-synucleinopathies

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28 July 2018

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α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system

28 July 2018

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α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

28 July 2018

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28 July 2018

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α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease

28 July 2018

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28 July 2018

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Alpha-synuclein stimulation of astrocytes: Potential role for neuroinflammation and neuroprotection

28 July 2018

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28 July 2018

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Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy

28 July 2018

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28 July 2018

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28 July 2018

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Mechanisms of microbial traversal of the blood-brain barrier

28 July 2018

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Clearance and deposition of extracellular alpha-synuclein aggregates in microglia.

28 July 2018

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28 July 2018

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28 July 2018

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Astrocyte-endothelial interactions at the blood-brain barrier

28 July 2018

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Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein

28 July 2018

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Enhanced prospects for drug delivery and brain targeting by the choroid plexus-CSF route

28 July 2018

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Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

28 July 2018

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Molecular mechanisms of cerebrospinal fluid production

28 July 2018

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28 July 2018

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Brain barrier systems: a new frontier in metal neurotoxicological research

28 July 2018

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Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

28 July 2018

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Establishment and characterization of an immortalized Z310 choroidal epithelial cell line from murine choroid plexus.

28 July 2018

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A role for alpha-synuclein in the regulation of dopamine biosynthesis

28 July 2018

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Neuropathology of synuclein aggregates

28 July 2018

1 reference

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

28 July 2018

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Synucleins in synaptic plasticity and neurodegenerative disorders

28 July 2018

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Parkinson's disease: dopaminergic nerve cell model is consistent with experimental finding of increased extracellular transport of α-synuclein.

28 July 2018

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A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Dangerous duet: LRRK2 and α-synuclein jam at CMA.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Mind the gut: secretion of α-synuclein by enteric neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Physiology and pathophysiology of the blood-brain barrier: P-glycoprotein and occludin trafficking as therapeutic targets to optimize central nervous system drug delivery

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

α-Synuclein: membrane interactions and toxicity in Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Genetic neuropathology of Parkinson's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Peripheral blood alpha-synuclein mRNA levels are elevated in cynomolgus monkeys that chronically self-administer ethanol

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Expression of alpha-synuclein, the precursor of non-amyloid beta component of Alzheimer's disease amyloid, in human cerebral blood vessels

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120720

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

29 October 2018

1 reference

12 December 2020

NACP/alpha-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson's disease brains

1 reference

12 December 2020

Mitochondrial dysfunction in Parkinson's disease

1 reference

12 December 2020

Effect of metals on herbicides-alpha-synuclein association: a possible factor in neurodegenerative disease studied by capillary electrophoresis

1 reference

12 December 2020

Identifiers

DOI

10.1186/2045-8118-11-17

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Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

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