(Q40405368)

PubMed publication ID

15976091

20 September 2017

title

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

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3

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author name string

He-Jin Lee

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

Smita Patel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

Seung-Jae Lee

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

language of work or name

English

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publication date

1 June 2005

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PubMed publication ID

15976091

20 September 2017

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

issue

25

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

page(s)

6016-6024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

12 May 2020

cites work

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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12 December 2020

A Drosophila model of Parkinson's disease

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12 December 2020

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12 December 2020

alpha-Synuclein membrane interactions and lipid specificity

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12 December 2020

An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles

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12 December 2020

Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein

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12 December 2020

Saponin permeabilization of rough microsomes from rat liver reveals a novel prothrombin pool

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12 December 2020

Alpha-synuclein and neurodegenerative diseases

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12 December 2020

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

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12 December 2020

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

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12 December 2020

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

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12 December 2020

Intra- and intercellular trafficking of the foamy virus auxiliary bet protein

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12 December 2020

Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease?

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12 December 2020

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

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12 December 2020

Accelerated alpha-synuclein fibrillation in crowded milieu

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12 December 2020

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

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12 December 2020

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

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12 December 2020

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

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12 December 2020

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

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12 December 2020

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

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12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

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12 December 2020

A broken alpha -helix in folded alpha -Synuclein

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12 December 2020

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

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12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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12 December 2020

The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes

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12 December 2020

A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins

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12 December 2020

A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein

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12 December 2020

alpha-synuclein aggregation: a link between mitochondrial defects and Parkinson's disease?

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12 December 2020

Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease

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12 December 2020

Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway

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12 December 2020

Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma

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12 December 2020

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

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12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

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12 December 2020

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

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12 December 2020

Yeast cells provide insight into alpha-synuclein biology and pathobiology

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12 December 2020

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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12 December 2020

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

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12 December 2020

Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

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12 December 2020

Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication

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12 December 2020

Exosomes: endosomal-derived vesicles shipping extracellular messages

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12 December 2020

Lipid rafts mediate the synaptic localization of alpha-synuclein.

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12 December 2020

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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12 December 2020

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

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12 December 2020

Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein

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12 December 2020

alpha-Synuclein produces a long-lasting increase in neurotransmitter release

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12 December 2020

Calcium(II) selectively induces alpha-synuclein annular oligomers via interaction with the C-terminal domain

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12 December 2020

Role of alpha-synuclein in presynaptic dopamine recruitment.

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12 December 2020

Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

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12 December 2020

Alpha-synuclein targets the plasma membrane via the secretory pathway and induces toxicity in yeast

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12 December 2020

A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence

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12 December 2020

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

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12 December 2020

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

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12 December 2020

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

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12 December 2020

Neuropathology of Parkinson's disease

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12 December 2020

Intercellular trafficking and protein delivery by a herpesvirus structural protein

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12 December 2020

Occurrence of two types of secretory vesicles in the human neuroblastoma SH-SY5Y.

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

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12 December 2020

10.1523/JNEUROSCI.0692-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6724798&resulttype=core&format=json

12 May 2020

PubMed publication ID

15976091

1 reference