(Q46111700)

19 December 2017

title

Accelerated alpha-synuclein fibrillation in crowded milieu (English)

1 reference

19 December 2017

1 reference

1 reference

1

Vladimir N Uversky

0 references

author name string

Vladimir N Uversky

1

1 reference

19 December 2017

Elisa M Cooper

2

1 reference

19 December 2017

Kiowa S Bower

3

1 reference

19 December 2017

Jie Li

4

1 reference

19 December 2017

Anthony L Fink

5

1 reference

19 December 2017

language of work or name

English

0 references

publication date

1 March 2002

1 reference

19 December 2017

published in

FEBS Letters

1 reference

19 December 2017

volume

515

1 reference

19 December 2017

page(s)

99-103

1 reference

19 December 2017

issue

1-3

1 reference

19 December 2017

Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

How crowded is the cytoplasm?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Living with water stress: evolution of osmolyte systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Influence of excluded volume upon macromolecular structure and associations in 'crowded' media

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Implications of macromolecular crowding for protein assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Effect of a concentrated "inert" macromolecular cosolute on the stability of a globular protein with respect to denaturation by heat and by chaotropes: a statistical-thermodynamic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Molecular confinement influences protein structure and enhances thermal protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Crowding and hydration effects on protein conformation: a study with sol-gel encapsulated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

The effect of molecular confinement on the conformational dynamics of the native and partly folded state of apomyoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Effects of crowding by mono-, di-, and tetrasaccharides on cytochrome c-cytochrome c peroxidase binding: comparing experiment to theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Identification of two distinct synucleins from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Conformational properties of alpha-synuclein in its free and lipid-associated states

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Alpha-synuclein and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Synthetic filaments assembled from C-terminally truncated alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Use of fast protein size-exclusion liquid chromatography to study the unfolding of proteins which denature through the molten globule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902446-8

10.1016/S0014-5793(02)02446-8

7 January 2021

Identifiers

DOI

1 reference

19 December 2017

PubMed ID

11943202

1 reference

19 December 2017