(Q34000068)

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Generation of multinucleated giant cells in vitro by culture of human monocytes with Mycobacterium bovis BCG in combination with cytokine-containing supernatants

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7 December 2019

Generation of multinucleated giant cells in vitro by culture of human monocytes with Mycobacterium bovis BCG in combination with cytokine-containing supernatants (English)

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Europe PubMed Central

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7 December 2019

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Mycobacterium bovis

object named as

Mycobacterium bovis

1 reference

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author name string

A Gasser

1

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7 December 2019

J Möst

2

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7 December 2019

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publication date

1 January 1999

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7 December 2019

Infection and Immunity

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7 December 2019

67

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7 December 2019

1

1 reference

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7 December 2019

395-402

1 reference

Europe PubMed Central

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7 December 2019

Mycobacterial growth and sensitivity to H2O2 killing in human monocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis.

1 reference

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5 July 2018

Nonopsonic binding of Mycobacterium tuberculosis to human complement receptor type 3 expressed in Chinese hamster ovary cells

1 reference

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5 July 2018

T- and B-lymphocyte-independent formation of alveolar macrophage-derived multinucleated giant cells in murine Pneumocystis carinii pneumonia

1 reference

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5 July 2018

Immunopathology of tuberculosis: roles of macrophages and monocytes

1 reference

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5 July 2018

Inability of normal human intestinal macrophages to form multinucleated giant cells in response to cytokines.

1 reference

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5 July 2018

Detection of tumour necrosis factor alpha in sarcoidosis and tuberculosis granulomas using in situ hybridisation

1 reference

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5 July 2018

Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor

1 reference

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5 July 2018

Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Mycobacterium tuberculosis alters expression of adhesion molecules on monocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Kinetics and ultrastructural studies of the induction of rat alveolar macrophage fusion by mediators released from mitogen-stimulated lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Formation of multinucleated giant cells from human monocyte precursors. Mediation by a soluble protein from antigen-and mitogen-stimulated lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Recombinant human gamma-interferon induces human monocyte polykaryon formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Transformation of hamster macrophages into giant cells with antimacrophage serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Fusion of normal rabbit alveolar macrophages induced by supernatant fluids from BCG-sensitized lymph node cells after elicitation by antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Recombinant human interferon-gamma inhibits formation of human osteoclast-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Multinucleated giant cells generated in vitro. Terminally differentiated macrophages with down-regulated c-fms expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Granuloma formation by artificial microparticles in vitro. Macrophages and monokines play a critical role in granuloma formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Cytokine-induced generation of multinucleated giant cells in vitro requires interferon-gamma and expression of LFA-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Granulocyte-macrophage colony-stimulating factor is a major macrophage fusion factor present in conditioned medium of concanavalin A-stimulated spleen cell cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Induction of Multinucleated Giant Cell Formation from In Vitro Culture of Human Monocytes with Interleukin-3 and Interferon-γ: Comparison with Other Stimulating Factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Role of IL-4 and IFN-gamma in Schistosoma mansoni egg-induced hypersensitivity granuloma formation. Orchestration, relative contribution, and relationship to macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Failure of altered macrophage surface to lead to the formation of polykaryons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

The mechanism of fusion of hamster macrophages induced by antimacrophage serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Macrophage fusion and multinucleated giant cell formation, surface morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

The tumoricidal properties of inflammatory tissue macrophages and multinucleate giant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

5 July 2018

Lymphokine induction of rat microglia multinucleated giant cell formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

29 October 2018

Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T cell clones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

29 October 2018

Interleukin 4 and human immunodeficiency virus stimulate LFA-1-ICAM-1-mediated aggregation of monocytes and subsequent giant cell formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

29 October 2018

Influence of mycobacterial virulence and culture condition on γδ T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96322

29 October 2018

Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarized distribution of Na+,K+-ATPase in giant cells elicited in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-RMA, a murine monoclonal antibody, activates rat macrophages: II. Induction of DNA synthesis and formation of multinucleated giant cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant murine interferon-gamma inhibits the fusion of mouse alveolar macrophages in vitro but stimulates the formation of osteoclastlike cells on implanted syngeneic bone particles in mice in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of fusion regulatory proteins (FRPs) on human peripheral blood monocytes. Induction of homotypic cell aggregation and formation of multinucleated giant cells by anti-FRP-1 monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multinucleated giant cells generation induced by interferon-gamma. Changes in the expression and distribution of the intercellular adhesion molecule-1 during macrophages fusion and multinucleated giant cell formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The formation and properties of macrophage polykaryons (inflammatory giant cells)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion of macrophages following simultaneous attempted phagocytosis of glutaraldehyde-fixed red cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion of hamster macrophages induced by lectins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of gelatin/plasma coated flasks for isolating human peripheral blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion and activation of human alveolar macrophages induced by recombinant interferon-gamma and their suppression by dexamethasone

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-class II MHC antibody induces multinucleated giant cell formation from peripheral blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of formation of multinucleated giant cells from concanavalin A-stimulated human blood monocytes by IFN-gamma and IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCP-1-stimulated monocytes preferentially utilize beta 2-integrins to migrate on laminin and fibronectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multinucleated giant cell formation of swine microglia induced by Mycobacterium bovis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte aggregation and multinucleated giant-cell formation in vitro in Crohn's disease. The effect of cell adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M-CSF and GM-CSF promote alveolar macrophage differentiation into multinucleated giant cells with distinct phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of multinucleated giant cells in vitro is dependent on the stage of monocyte to macrophage maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of multinucleated giant cells by culture of monocyte-derived macrophages with IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human in vitro granuloma model using heat killed Candida albicans cells immobilized on plastic culture wells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probable in vivo Origin of Multi-Nucleated Giant Cells from Circulating Mononuclears

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular evolution of inflammatory granulomata

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mycobacteria-macrophage interactions. Macrophage phenotype determines the nonopsonic binding of Mycobacterium tuberculosis to murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9864241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.67.1.395-402.1999

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9864241%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9864241%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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