(Q34000146)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

title

Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

main subject

Clostridium difficile

0 references

1 reference

6

T P Monath

2 references

PubMed publication ID

9916055

30 July 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

author name string

P J Giannasca

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

Z X Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

W D Lei

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

J A Boden

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

M A Giel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

W D Thomas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

language of work or name

English

0 references

publication date

1 February 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

published in

Infection and Immunity

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

volume

67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

issue

2

1 reference

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9 December 2019

page(s)

527-538

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection.

9 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Detoxification of the Helicobacter pylori cytotoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Targeted delivery of antigen to hamster nasal lymphoid tissue with M-cell-directed lectins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Comparison of the oral, rectal, and vaginal immunization routes for induction of antibodies in rectal and genital tract secretions of women

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Large clostridial cytotoxins--a family of glycosyltransferases modifying small GTP-binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Effects of Clostridium difficile toxin B on human monocytes and macrophages: possible relationship with cytoskeletal rearrangement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Clostridium difficile diarrhea: pathogenesis, epidemiology, and treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Perspective: hypothesis: serum IgG antibody is sufficient to confer protection against infectious diseases by inactivating the inoculum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Selective neutralization of a bacterial enterotoxin by serum immunoglobulin A in response to mucosal disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Clearance of Pseudomonas aeruginosa from the murine gastrointestinal tract is effectively mediated by O-antigen-specific circulating antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Production of Clostridium difficile antitoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Neutralizing activity against Clostridium difficile toxin in the supernatants of cultured colostral cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Rapid death of infant rhesus monkeys injected with Clostridium difficile toxins A and B: physiologic and pathologic basis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Enzyme-linked immunosorbent assay for Clostridium difficile toxin A

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Effects of Clostridium difficile toxins given intragastrically to animals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Immunization of adult hamsters against Clostridium difficile-associated ileocecitis and transfer of protection to infant hamsters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Nosocomial acquisition of Clostridium difficile infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Passive immunization of hamsters against disease caused by Clostridium difficile by use of bovine immunoglobulin G concentrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Cytokine response by human monocytes to Clostridium difficile toxin A and toxin B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Protection against experimental pseudomembranous colitis in gnotobiotic mice by use of monoclonal antibodies against Clostridium difficile toxin A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=96351

Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore

29 October 2018

1 reference

12 December 2020

In vitro and in vivo neutralizing activity of human colostrum and milk against purified toxins A and B of Clostridium difficile

1 reference

12 December 2020

Active and passive immunization to protect against antibiotic associated caecitis in hamsters

1 reference

12 December 2020

Serum antibody response to toxins A and B of Clostridium difficile

1 reference

12 December 2020

Gamma globulin administration in relapsing Clostridium difficile-induced pseudomembranous colitis with a defective antibody response to toxin A

1 reference

12 December 2020

Prevention of clindamycin-induced colitis in hamsters by Clostridium sordellii antitoxin

1 reference

12 December 2020

Increased length of hospital stay due to Clostridium difficile associated diarrhoea

1 reference

12 December 2020

Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity

1 reference

12 December 2020

Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamsters

1 reference

12 December 2020

Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9916055%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

9916055

1 reference