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The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
title
The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
author
Cathy Tournier
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
Katherine G Finegan
object named as
Katherine G Finegan
series ordinal
1
1 reference
stated in
ORCID Public Data File 2021
language of work or name
English
0 references
publication date
7 July 2010
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
published in
Cancer Research
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
volume
70
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
issue
14
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
page(s)
5797-5806
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
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PubMed Central
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Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death
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5 July 2018
Role of mitogen-activated protein kinase kinase 4 in cancer
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PubMed Central
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Physiological roles of MKK4 and MKK7: insights from animal models
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Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss
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Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors
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5 July 2018
Transcriptional regulation by the MAP kinase signaling cascades
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5 July 2018
c-Jun regulates eyelid closure and skin tumor development through EGFR signaling
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Role of JNK in tumor development
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Suppression of Ras-stimulated transformation by the JNK signal transduction pathway
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5 July 2018
Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.
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5 July 2018
Differential gene expression profiles of Jnk1- and Jnk2-deficient murine fibroblast cells.
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5 July 2018
Targeted somatic mutagenesis in mouse epidermis
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5 July 2018
Jun, the oncoprotein.
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5 July 2018
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.
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5 July 2018
Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers
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PubMed Central
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5 July 2018
Human gastric cancer kinase profile and prognostic significance of MKK4 kinase
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PubMed Central
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5 July 2018
Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
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5 July 2018
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
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PubMed Central
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5 July 2018
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5 July 2018
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5 July 2018
Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene
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PubMed Central
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5 July 2018
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5 July 2018
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5 July 2018
Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites
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5 July 2018
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
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PubMed Central
reference URL
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5 July 2018
Selective regulation of c-jun gene expression by mitogen-activated protein kinases via the 12-o-tetradecanoylphorbol-13-acetate- responsive element and myocyte enhancer factor 2 binding sites.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
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29 October 2018
MAP2K4/MKK4 expression in pancreatic cancer: genetic validation of immunohistochemistry and relationship to disease course.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
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29 October 2018
Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
retrieved
29 October 2018
Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
retrieved
29 October 2018
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906708
retrieved
29 October 2018
JNK2 is a positive regulator of the cJun transcription factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20610622
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20610622
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20610622
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/0008-5472.CAN-09-3669
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PMCID
2906708
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PubMed ID
20610622
1 reference
stated in
Europe PubMed Central
PMCID
2906708
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610622%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
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