(Q34008085)

30 July 2017

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title

SUMO4 and its role in type 1 diabetes pathogenesis (English)

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30 July 2017

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Cong-Yi Wang

1

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30 July 2017

Jin-Xiong She

series ordinal

2

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30 July 2017

publication date

1 February 2008

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Diabetes - Metabolism: Research and Reviews

30 July 2017

published in

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30 July 2017

volume

24

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30 July 2017

issue

2

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30 July 2017

page(s)

93-102

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Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins

30 July 2017

cites work

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Transcriptional Regulation of Type I Diabetes by NF-κB

21 January 2018

1 reference

Suppression of STAT3 activity by Duplin, which is a negative regulator of the Wnt signal

21 January 2018

1 reference

The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

Screening for genetic IDDM risk and prevention trials in infancy

21 January 2018

1 reference

7 January 2021

Distinct genetic and immunological features in patients with onset of IDDM before and after age 40

1 reference

7 January 2021

Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States

1 reference

7 January 2021

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

1 reference

7 January 2021

A genome-wide search for human type 1 diabetes susceptibility genes

1 reference

7 January 2021

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

1 reference

7 January 2021

Saturation multipoint linkage mapping of chromosome 6q in type 1 diabetes

1 reference

7 January 2021

Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene

1 reference

7 January 2021

Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

1 reference

7 January 2021

Genetic heterogeneity in association of the SUMO4 M55V variant with susceptibility to type 1 diabetes

1 reference

7 January 2021

Abnormal expression of CTLA-4 by T cells from patients with myasthenia gravis: effect of an AT-rich gene sequence

1 reference

7 January 2021

A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes

1 reference

7 January 2021

Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

1 reference

7 January 2021

Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

1 reference

7 January 2021

SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients

1 reference

7 January 2021

Molecular aspects of type 1 diabetes

1 reference

7 January 2021

The role of vitamin D in protecting type 1 diabetes mellitus

1 reference

7 January 2021

Susceptibility to type I diabetes: HLA-DQ and DR revisited

1 reference

7 January 2021

SUMO wrestling with type 1 diabetes

1 reference

7 January 2021

A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus

1 reference

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

7 January 2021

SUMO, ubiquitin's mysterious cousin

1 reference

7 January 2021

Structure determination of the small ubiquitin-related modifier SUMO-1

1 reference

7 January 2021

Global shifts in protein sumoylation in response to electrophile and oxidative stress.

1 reference

7 January 2021

Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

1 reference

7 January 2021

The PML-nuclear inclusion of human supraoptic neurons: a new compartment with SUMO-1- and ubiquitin-proteasome-associated domains.

1 reference

7 January 2021

Positive and negative regulation of APP amyloidogenesis by sumoylation.

1 reference

7 January 2021

Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development.

1 reference

7 January 2021

SUMO modification of Huntingtin and Huntington's disease pathology

1 reference

7 January 2021

The NF-kappaB pathway as a potential target for autoimmune disease therapy

1 reference

7 January 2021

Antioxidants, NFkappaB activation, and diabetogenesis

1 reference

7 January 2021

NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes

1 reference

7 January 2021

Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity

1 reference

7 January 2021

Autoimmune destruction of pancreatic beta cells.

1 reference

7 January 2021

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

7 January 2021

Signaling through the JAK/STAT pathway, recent advances and future challenges

1 reference

7 January 2021

Role of the JAK/STAT signaling pathway in diabetic nephropathy.

1 reference

7 January 2021

JAK/STAT signal transduction: regulators and implication in hematological malignancies

1 reference

7 January 2021

JANUS under stress--role of JAK/STAT signaling pathway in vascular diseases

1 reference

7 January 2021

Regulation of gene-activation pathways by PIAS proteins in the immune system

1 reference

7 January 2021

A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases

1 reference

7 January 2021

PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes

1 reference

7 January 2021

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

1 reference

7 January 2021

PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription

1 reference

7 January 2021

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

1 reference

7 January 2021

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

1 reference

7 January 2021

PIAS proteins promote SUMO-1 conjugation to STAT1

1 reference

7 January 2021

FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family.

1 reference

7 January 2021

SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation

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7 January 2021

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

1 reference

7 January 2021

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

1 reference

7 January 2021

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

7 January 2021

Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines

1 reference

7 January 2021

Interleukin-1beta activates a short STAT-3 isoform in clonal insulin-secreting cells

1 reference

7 January 2021

A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice

1 reference

7 January 2021

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

1 reference

7 January 2021

Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation

1 reference

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

7 January 2021

Genome-scale functional profiling of the mammalian AP-1 signaling pathway

1 reference

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

7 January 2021

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

1 reference

7 January 2021

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

1 reference

7 January 2021

Targeting transcription factors for cancer gene therapy.

1 reference

7 January 2021

AP-1 and colorectal cancer

1 reference

7 January 2021

AP-1 subunits: quarrel and harmony among siblings

1 reference

7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

7 January 2021

Development of autoreactive diabetogenic T cells in the thymus of NOD mice

1 reference

7 January 2021

TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway

1 reference

7 January 2021

c-fos proto-oncogene regulation and function

1 reference

7 January 2021

Differential directing of c-Fos and c-Jun proteins to the proteasome in serum-stimulated mouse embryo fibroblasts

1 reference

7 January 2021

c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

1 reference

7 January 2021

The structural determinants responsible for c-Fos protein proteasomal degradation differ according to the conditions of expression.

1 reference

7 January 2021

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

7 January 2021

SUMO: a regulator of gene expression and genome integrity.

1 reference

7 January 2021

SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1

1 reference

7 January 2021

Serum response factor is modulated by the SUMO-1 conjugation system

1 reference

7 January 2021

Approaches to type 1 diabetes prevention by intervention in cytokine immunoregulatory circuits

1 reference

7 January 2021

Prevention of type 1 diabetes: from the view point of beta cell damage

1 reference

7 January 2021

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

1 reference

7 January 2021

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

1 reference

7 January 2021

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

7 January 2021

Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

1 reference

7 January 2021

Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

1 reference

7 January 2021

Adenoviral overexpression of the glutamylcysteine ligase catalytic subunit protects pancreatic islets against oxidative stress

1 reference

7 January 2021

Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells

1 reference

7 January 2021

Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors.

1 reference

7 January 2021

Cytoprotection of beta cells: rational gene transfer strategies

1 reference

7 January 2021

Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses

1 reference

7 January 2021

SUMO modification of Sam68 enhances its ability to repress cyclin D1 expression and inhibits its ability to induce apoptosis

1 reference

7 January 2021

Induction of apoptosis increases SUMO-1 protein expression and conjugation in mouse periovulatory granulosa cells in vitro.

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7 January 2021

SUMO-1 represses apoptosis signal-regulating kinase 1 activation through physical interaction and not through covalent modification

1 reference

7 January 2021

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population

1 reference

7 January 2021

SUMO4 M55V variant is associated with diabetic nephropathy in type 2 diabetes

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.797

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30 July 2017

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