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Mammalian MAP kinase signalling cascades
scientific article (publication date: March 2001)
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instance of
scholarly article
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review article
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Europe PubMed Central
title
Mammalian MAP kinase signalling cascades
(English)
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author name string
L Chang
series ordinal
1
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M Karin
series ordinal
2
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language of work or name
English
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publication date
1 March 2001
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published in
Nature
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volume
410
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page(s)
37-40
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issue
6824
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cites work
New insights into the control of MAP kinase pathways
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7 January 2021
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inferred from DOI database lookup
Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.
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7 January 2021
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MAP kinase pathways in yeast: for mating and more
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7 January 2021
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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.
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7 January 2021
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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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A mammalian scaffold complex that selectively mediates MAP kinase activation
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MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg.
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7 January 2021
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c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions
1 reference
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7 January 2021
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A conserved docking motif in MAP kinases common to substrates, activators and regulators
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7 January 2021
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Regulation of transcription by MAP kinase cascades
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7 January 2021
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Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
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7 January 2021
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Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
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7 January 2021
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MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
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7 January 2021
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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E
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Regulation of carbamoyl phosphate synthetase by MAP kinase
1 reference
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7 January 2021
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A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.
1 reference
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The protein kinase p90 rsk as an essential mediator of cytostatic factor activity.
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Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk.
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7 January 2021
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Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest
1 reference
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7 January 2021
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inferred from DOI database lookup
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Selective requirement for MAP kinase activation in thymocyte differentiation.
1 reference
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7 January 2021
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inferred from DOI database lookup
Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
based on heuristic
inferred from DOI database lookup
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
c-Jun is essential for normal mouse development and hepatogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
based on heuristic
inferred from DOI database lookup
JNK is involved in signal integration during costimulation of T lymphocytes.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Defective T Cell Differentiation in the Absence of Jnk1
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.
1 reference
stated in
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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inferred from DOI database lookup
JNK is required for effector T-cell function but not for T-cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35065000
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35065000
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
1 reference
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https://api.crossref.org/works/10.1038%2F35065000
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7 January 2021
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Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35065000
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35065000
retrieved
7 January 2021
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inferred from DOI database lookup
Identifiers
DOI
10.1038/35065000
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
488638
Dimensions Publication ID
1029421135
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OpenCitations bibliographic resource ID
488638
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
488638
PubMed ID
11242034
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
488638
ResearchGate publication ID
12090245
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Springer Nature article ID
10.1038/35065000
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