(Q34008495)

30 July 2017

Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades (English)

1 reference

30 July 2017

3

1 reference

30 July 2017

Fernando Ortega

1

0 references

Francesc Mas

object named as

Francesc Mas

series ordinal

4

0 references

Marta Cascante Serratosa

object named as

Marta Cascante

series ordinal

5

0 references

author name string

Luis Acerenza

series ordinal

2

1 reference

PubMed ID

11830657

30 July 2017

language of work or name

English

0 references

publication date

1 February 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

99

1 reference

30 July 2017

1170-1175

1 reference

30 July 2017

3

1 reference

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Macromolecular intelligence in microorganisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Current topics in signal transduction in bacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

The control of filamentous differentiation and virulence in fungi.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Ultrasensitivity in the mitogen-activated protein kinase cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

An additional PII in Escherichia coli: a new regulatory protein in the glutamine synthetase cascade.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

An amplified sensitivity arising from covalent modification in biological systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Protein phosphorylation in the control of glycolysis and gluconeogenesis in the liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Sensitivity amplification in biochemical systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Characterization of a glutamine synthetase inactivating enzyme from Escherichiacoli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Mechanism of the enzymatic inactivation of glutamine synthetase from E. coli.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Metabolic control and its analysis. Additional relationships between elasticities and control coefficients.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Zero-order ultrasensitivity in the regulation of glycogen phosphorylase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

How do external parameters control fluxes and concentrations of metabolites? An additional relationship in the theory of metabolic control.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Metabolic control theory: a structural approach.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Characteristics necessary for an interconvertible enzyme cascade to generate a highly sensitive response to an effector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Regulation of Escherichia coli glutamine synthetase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. II. Complex systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. I. Unbranched pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Enzyme-enzyme interactions and control analysis. 2. The case of non-independence: heterologous associations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Enzyme-enzyme interactions and control analysis. 1. The case of non-additivity: monomer-oligomer associations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Covalent modification and metabolic control analysis. Modification to the theorems and their application to metabolic systems containing covalently modifiable enzymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Quantitative assessment of regulation in metabolic systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Control theory of regulatory cascades.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Control of the metabolic flux in a system with high enzyme concentrations and moiety-conserved cycles. The sum of the flux control coefficients can drop significantly below unity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Superiority of interconvertible enzyme cascades in metabolic regulation: analysis of monocyclic systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Superiority of interconvertible enzyme cascades in metabolic regulation: Analysis of multicyclic systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122162

Reciprocal Relations in Irreversible Processes. I

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Response coefficients of interconvertible enzyme cascades towards effectors that act on one or both modifier enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

How do enzyme activities control metabolite concentrations? An additional theorem in the theory of metabolic control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Metabolic control design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Design of large metabolic responses. Constraints and sensitivity analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

The control of enzyme systems in vivo: elasticity analysis of the steady state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

An alternative PII protein in the regulation of glutamine synthetase in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Getting to the inside of cells using metabolic control analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Defining control coefficients in non-ideal metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Sensitivity constraints in a chemical/biochemical highly responsive system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Metabolic design: How to engineer a living cell to desired metabolite concentrations and fluxes

21 January 2018

2 references

https://api.crossref.org/works/10.1073%2FPNAS.022267399

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/11830657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

How constrained is metabolic control?

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.022267399

Why do protein kinase cascades have more than one level?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11830657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Energy consumption in a cyclic phosphorylation/dephosphorylation cascade

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11830657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.022267399

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

11830657