(Q34013543)

30 July 2017

title

Neurotoxic effects of TDP-43 overexpression in C. elegans (English)

1 reference

Defective pharyngeal development protein 4 CELE_F38A6.1

30 July 2017

main subject

Caenorhabditis elegans

0 references

neurotoxicity

1 reference

based on heuristic

inferred from title

1 reference

GOA release 2020-03-11

1 reference

Emanuele Buratti

6

0 references

Leonard Petrucelli

7

object named as

Leonard Petrucelli

1 reference

30 July 2017

5

Harald Hutter

1 reference

30 July 2017

Peter E A Ash

1

1 reference

30 July 2017

Yong-Jie Zhang

2

1 reference

30 July 2017

Christine M Roberts

3

1 reference

30 July 2017

Tassa Saldi

4

1 reference

30 July 2017

Christopher D Link

8

1 reference

30 July 2017

publication date

8 June 2010

1 reference

30 July 2017

published in

Human Molecular Genetics

1 reference

30 July 2017

volume

19

1 reference

30 July 2017

issue

16

1 reference

30 July 2017

page(s)

3206-3218

1 reference

A Drosophila model for TDP-43 proteinopathy

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

5 July 2018

1 reference

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Clinical and pathological continuum of multisystem TDP-43 proteinopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Structural determinants of the cellular localization and shuttling of TDP-43.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Missense, nonsense, and neutral mutations define juxtaposed regulatory elements of splicing in cystic fibrosis transmembrane regulator exon 9.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

lin-14 regulates the timing of synaptic remodelling in Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Genes required for GABA function in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908471

Programmed cell death in Caenorhabditis elegans

29 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ230

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20530643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDQ230

1 reference

30 July 2017

1 reference

30 July 2017

1 reference