(Q34013850)

30 July 2017

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title

Fast, hungry and unstable: finding the Achilles' heel of small-cell lung cancer (English)

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30 July 2017

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Charles M Rudin

2

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author name string

Christine L Hann

series ordinal

1

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30 July 2017

publication date

26 February 2007

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Trends in Molecular Medicine

30 July 2017

published in

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30 July 2017

volume

13

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30 July 2017

issue

4

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30 July 2017

page(s)

150-157

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Phase II trial of imatinib maintenance therapy after irinotecan and cisplatin in patients with c-Kit-positive, extensive-stage small-cell lung cancer

30 July 2017

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions

28 July 2018

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CD117 (c-KIT) overexpression in patients with extensive-stage small-cell lung carcinoma

28 July 2018

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Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression

28 July 2018

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Clinical development of mammalian target of rapamycin inhibitors

28 July 2018

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Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer

28 July 2018

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28 July 2018

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Effects of Bcl-2 and Bcl-XL protein levels on chemoresistance of hepatoblastoma HepG2 cell line

28 July 2018

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HGF: a multifunctional growth factor controlling cell scattering.

28 July 2018

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Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer

28 July 2018

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The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway.

28 July 2018

1 reference

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Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence

28 July 2018

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Differential retinoblastoma protein expression in neuroendocrine tumors of the lung. Potential diagnostic implications

28 July 2018

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Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095.

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Thalidomide is an inhibitor of angiogenesis

28 July 2018

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Expression of the gastrin-releasing peptide gene in human small cell lung cancer. Evidence for alternative processing resulting in three distinct mRNAs

28 July 2018

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Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

28 July 2018

1 reference

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Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule

28 July 2018

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Telomeres shorten during ageing of human fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Psi 13,14 bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Production of neuromedin B and neuromedin B gene expression in human lung tumor cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors

28 July 2018

1 reference

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Reduction in BCL-2 levels by 26S proteasome inhibition with bortezomib is associated with induction of apoptosis in small cell lung cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Imatinib mesylate lacks activity in small cell lung carcinoma expressing c-kit protein: a phase II clinical trial

29 October 2018

1 reference

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Vascular endothelial growth factor level as a prognostic determinant of small cell lung cancer in Japanese patients

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Phase I-II study of amrubicin and cisplatin in previously untreated patients with extensive-stage small-cell lung cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Angiogenesis inhibitors in the treatment of small cell and non-small cell lung cancer.

29 October 2018

1 reference

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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Phase I study of G3139, a bcl-2 antisense oligonucleotide, combined with carboplatin and etoposide in patients with small-cell lung cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Phase II study of imatinib in patients with small cell lung cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Expression and prognostic significance of kit, protein kinase B, and mitogen-activated protein kinase in patients with small cell lung cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Characterization of c-kit expression in small cell lung cancer: prognostic and therapeutic implications

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways

29 October 2018

1 reference

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Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy

29 October 2018

1 reference

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Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the Europea

29 October 2018

1 reference

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Chromosomal imbalances in human lung cancer

29 October 2018

1 reference

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Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells.

29 October 2018

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An effective immunization and cancer treatment with activated dendritic cells transduced with full-length wild-type p53.

29 October 2018

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Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.

29 October 2018

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Phase I and imaging trial of a monoclonal antibody directed against gastrin-releasing peptide in patients with lung cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

A new antitumor agent amrubicin induces cell growth inhibition by stabilizing topoisomerase II-DNA complex.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124625

Serum vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) levels in small cell lung cancer

29 October 2018

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12 December 2020

Phase II study of amrubicin in previously untreated patients with extensive-disease small cell lung cancer: West Japan Thoracic Oncology Group (WJTOG) study

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12 December 2020

Phase III double-blind, placebo-controlled study of thalidomide in extensive-disease small-cell lung cancer after response to chemotherapy: an intergroup study FNCLCC cleo04 IFCT 00-01

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12 December 2020

Reactivity of monoclonal antibodies with ganglioside antigens in human small cell lung cancer tissues

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12 December 2020

Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571

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12 December 2020

Immunophenotype of small cell lung carcinoma. Expression of NKH-1 and transferrin receptor and absence of most myeloid antigens

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12 December 2020

Multiple protein kinase pathways are involved in gastrin-releasing peptide receptor-regulated secretion

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12 December 2020

Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo

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12 December 2020

High prevalence of bcl-2 oncoprotein expression in small cell lung cancer

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12 December 2020

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines

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12 December 2020

Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas

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12 December 2020

Ganglioside expression in lung cancer cell lines

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12 December 2020

Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guérin

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12 December 2020

Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses

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12 December 2020

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

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12 December 2020

Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer

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12 December 2020

Small cell lung cancer clinical practice guidelines in oncology

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12 December 2020

10.1016/J.MOLMED.2007.02.003

Identifiers

DOI

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30 July 2017

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30 July 2017

1 reference