(Q34018715)

30 July 2017

0 references

Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis? (English)

1 reference

30 July 2017

1 reference

1 reference

1

Be'eri Niego

1 reference

30 July 2017

Robert L Medcalf

2

1 reference

PubMed ID

24896566

30 July 2017

language of work or name

1 reference

4 June 2014

1 reference

Journal of Cerebral Blood Flow & Metabolism

30 July 2017

1 reference

30 July 2017

34

1 reference

30 July 2017

8

1 reference

30 July 2017

1283-1296

1 reference

Improved method for the preparation of a human cell-based, contact model of the blood-brain barrier.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Optical imaging to map blood-brain barrier leakage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Hemostasis and alterations of the central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF-MMP pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasminogen receptors: the first quarter century

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasmin Activation of Glial Cells through Protease-Activated Receptor 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

A Rho kinase (ROCK) inhibitor, fasudil, prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasmin as a proinflammatory cell activator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Pharmacokinetics of alteplase in the treatment of ischaemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Annexin A2 promotes glioma cell invasion and tumor progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Structure, function and pathophysiology of protease activated receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The plasmin-antiplasmin system: structural and functional aspects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasmin on adherent cells: from microvesiculation to apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Increasing tPA activity in astrocytes induced by multipotent mesenchymal stromal cells facilitate neurite outgrowth after stroke in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Blood-brain barrier permeability and tPA-mediated neurotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Recombinant tissue plasminogen activator increases blood-brain barrier disruption in acute ischemic stroke: an MR imaging permeability study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Antiplasmin: the forgotten serpin?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Molecular mechanisms of fibrinolysis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

5 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The cardiovascular actions of protease-activated receptors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator: a historical perspective and personal account

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Rapid loss of microvascular integrin expression during focal brain ischemia reflects neuron injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Rapid differential endogenous plasminogen activator expression after acute middle cerebral artery occlusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasminogen enhances the secretion of plasminogen activator inhibitor-1 from cultured rat astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Transforming growth factor-beta mediates astrocyte-specific regulation of brain endothelial anticoagulant factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Ischaemic damage of brain microvessels: inherent risks for thrombolytic treatment in stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Neutral proteases and disruption of the blood-brain barrier in rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Degradation of human plasma and extracellular matrix fibronectin by tissue type plasminogen activator and urokinase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Extracellular proteolysis in the adult murine brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Tissue plasminogen activator for acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Plasminogen activator in the rodent brain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Basement membrane type IV collagen degradation: evidence for the involvement of a proteolytic cascade independent of metalloproteinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Hemorrhagic transformation following tissue plasminogen activator in experimental cerebral infarction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

The plasminogen activator/plasmin system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

On the specific interaction between the lysine-binding sites in plasmin and complementary sites in α2-antiplasmin and in fibrinogen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Combined tissue plasminogen activator and an NK1 tachykinin receptor antagonist: an effective treatment for reperfusion injury following acute ischemic stroke in rats.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Free radical scavenger edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Neutralizing the neurotoxic effects of exogenous and endogenous tPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Characterization of the Murine Plasma Fibrinolytic System

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

LRP and alphavbeta3 mediate tPA activation of smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasminogen potentiates thrombin cytotoxicity and contributes to pathology of intracerebral hemorrhage in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasminogen activation in experimental permanent focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Spatiotemporal evolution of blood brain barrier damage and tissue infarction within the first 3h after ischemia onset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Effect of transient focal ischemia on blood-brain barrier permeability in the rat: correlation to cell injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasminogen expression in the neonatal and adult mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Induction of plasminogen in rat hippocampal pyramidal neurons by kainic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasminogen mRNA induction in the mouse brain after kainate excitation: codistribution with plasminogen activator inhibitor-2 (PAI-2) mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Binding of latent matrix metalloproteinase 9 to fibrin: activation via a plasmin-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

A study of the protection of plasmin from antiplasmin inhibition within an intact fibrin clot during the course of clot lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Inactivation of antiplasmin at low pH: evidence for the formation of latent molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Acidotoxicity in brain ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Acute tissue damage after injections of thrombin and plasmin into rat striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasmin induces endothelium-dependent nitric oxide-mediated relaxation in the porcine coronary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Identification of thrombin receptors in rat brain capillary endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFbeta3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Tissue plasminogen activator in central nervous system physiology and pathology.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Impairment of the blood-brain barrier: a potential surrogate delineating the determinants of cerebral bleeding caused by fibrinolytic drugs.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Perturbation of the integrity of the blood-brain barrier by fibrinolytic enzymes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4126105

Astrocytes induce blood–brain barrier properties in endothelial cells

29 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy†

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2014.99

Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

21 January 2018

1 reference

12 December 2020

Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group

1 reference

12 December 2020

Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis

1 reference

12 December 2020

Pharmacokinetics and haemostatic status during consecutive infusions of recombinant tissue-type plasminogen activator in patients with acute myocardial infarction

1 reference

12 December 2020

Contraction of human brain endothelial cells induced by thrombogenic and fibrinolytic factors. An in vitro cell culture model

1 reference

12 December 2020

Cell-surface plasminogen activation causes a retraction of in vitro cultured human umbilical vein endothelial cell monolayer

1 reference

12 December 2020

Laminin degradation by plasmin regulates long-term potentiation

1 reference

12 December 2020

Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes

1 reference

12 December 2020

Plasminogen activation in focal cerebral ischemia and reperfusion

1 reference

12 December 2020

Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism

1 reference

12 December 2020

Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes

1 reference

12 December 2020

Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit

1 reference

12 December 2020

Monitoring of plasmin and plasminogen activator activity in blood of patients under fibrinolytic treatment by reteplase

1 reference

12 December 2020

Studies on the specific fibrinolytic effect of human extrinsic (tissue-type) plasminogen activator in human blood and in various animal species in vitro

1 reference

12 December 2020

Comparative effects of microplasmin and tissue-type plasminogen activator (tPA) on cerebral hemorrhage in a middle cerebral artery occlusion model in mice

1 reference

12 December 2020

Different therapy options protecting microvasculature after experimental cerebral ischaemia and reperfusion

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

1 reference

12 December 2020

Plasminogen has a broad extrahepatic distribution

1 reference

12 December 2020

Involvement of Thrombolysis in Recombinant Tissue Plasminogen Activator-Induced Cerebral Hemorrhages and Effect on Infarct Volume and Postischemic Endothelial Function

1 reference

12 December 2020

Identifiers

DOI

10.1038/JCBFM.2014.99

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

24896566