(Q34021867)

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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

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Europe PubMed Central

PubMed publication ID

30 July 2017

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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fatty liver disease

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metabolic dysfunction–associated steatotic liver disease

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non-alcoholic fatty liver

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insulin resistance

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object named as

Matthew J Laye

8

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object named as

John P Thyfault

2

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10

object named as

Frank W Booth

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Europe PubMed Central

PubMed publication ID

30 July 2017

Catherine R Mikus

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object named as

Catherine R Mikus

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

R Scott Rector

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Grace M Uptergrove

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

E Matthew Morris

4

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Europe PubMed Central

PubMed publication ID

30 July 2017

Scott P Naples

5

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Europe PubMed Central

PubMed publication ID

30 July 2017

Sarah J Borengasser

6

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Europe PubMed Central

PubMed publication ID

30 July 2017

M Harold Laughlin

9

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Europe PubMed Central

PubMed publication ID

30 July 2017

Jamal A Ibdah

11

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Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

4 March 2010

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Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Hepatology

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Europe PubMed Central

PubMed publication ID

30 July 2017

52

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Europe PubMed Central

PubMed publication ID

30 July 2017

5

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Europe PubMed Central

PubMed publication ID

30 July 2017

727-736

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Europe PubMed Central

PubMed publication ID

30 July 2017

Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Insulin resistance and obesity in childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1 alpha: implications for metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Prevalence of fatty liver in children and adolescents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Hyperphagia and obesity of OLETF rats lacking CCK1 receptors: developmental aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Nonalcoholic fatty liver disease: from steatosis to cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

NASH: a mitochondrial disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Downregulation of the skeletal muscle pyruvate dehydrogenase complex in the Otsuka Long-Evans Tokushima Fatty rat both before and after the onset of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Mitochondrial adaptations to obesity-related oxidant stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Mitochondrial abnormalities in non-alcoholic steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Steatohepatitis: a tale of two "hits"?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

5 July 2018

Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Calorie restriction improves whole-body glucose disposal and insulin resistance in association with the increased adipocyte-specific GLUT4 expression in Otsuka Long-Evans Tokushima fatty rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070177

29 October 2018

Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CCl4 in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of and risk factors for hepatic steatosis in Northern Italy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic differentiation of distinct muscle types at the level of enzymatic organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20347174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JHEP.2009.11.030

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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