(Q34030885)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

main subject

angiogenesis inhibitor

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Andreas O Frank

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Luciana Marinelli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Sandro Cosconati

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Ettore Novellino

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Johannes G Beck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Lucas Doedens

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Horst Kessler

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

25 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

Angewandte Chemie International Edition

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

9496-9500

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21948451%20AND%20SRC:MED&resulttype=core&format=json

Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation

13 February 2020

cites work

1 reference

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Targeting integrins in malignant glioma

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Integrins: bidirectional, allosteric signaling machines

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Integrins as therapeutic targets: lessons and opportunities

21 January 2018

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Integrins in angiogenesis and lymphangiogenesis

21 January 2018

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Integrins in cancer: biological implications and therapeutic opportunities

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New perspectives in cell adhesion: RGD and integrins

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Ligand binding to integrins

21 January 2018

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N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

21 January 2018

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Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting

21 January 2018

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Alphavbeta3/alphavbeta5 integrins-FAK-RhoB: a novel pathway for hypoxia regulation in glioblastoma

21 January 2018

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Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

21 January 2018

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21 January 2018

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A reevaluation of integrins as regulators of angiogenesis

21 January 2018

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Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

21 January 2018

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The Homeobox Transcription Factor Hox D3 Promotes Integrin α5β1 Expression and Function during Angiogenesis

21 January 2018

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Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

21 January 2018

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Will integrin inhibitors have proangiogenic effects in the clinic?

21 January 2018

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N-methylation of peptides: a new perspective in medicinal chemistry

21 January 2018

1 reference

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Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster.

21 January 2018

1 reference

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Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning

21 January 2018

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Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies

21 January 2018

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Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

21 January 2018

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Multiple N-methylation by a designed approach enhances receptor selectivity

21 January 2018

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Solid-phase synthesis and characterization of N-methyl-rich peptides.

21 January 2018

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Solid-phase synthesis of oxathiocoraline by a key intermolecular disulfide dimer.

21 January 2018

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Optimized selective N-methylation of peptides on solid support

21 January 2018

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

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N-methylated cyclic pentaalanine peptides as template structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201102971

Conformational preference and potential templates of N-methylated cyclic pentaalanine peptides

21 January 2018

1 reference

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Pharmacophore refinement of gpIIb/IIIa antagonists based on comparative studies of antiadhesive cyclic and acyclic RGD peptides.

21 January 2018

1 reference

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