(Q34031817)

30 July 2017

title

Akt regulates IL-10 mediated suppression of TNFα-induced cardiomyocyte apoptosis by upregulating Stat3 phosphorylation (English)

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30 July 2017

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Ashim K Bagchi

2

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Sanjiv Dhingra

object named as

Sanjiv Dhingra

1

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author name string

Ana L Ludke

3

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30 July 2017

Anita K Sharma

4

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30 July 2017

Pawan K Singal

5

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30 July 2017

language of work or name

English

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publication date

20 September 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

9

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30 July 2017

page(s)

e25009

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

20 September 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Interleukin-10 modulates pro-apoptotic effects of TNF-alpha in human articular chondrocytes in vitro.

5 July 2018

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TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis

5 July 2018

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Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failu

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A mechanistic role for cardiac myocyte apoptosis in heart failure

5 July 2018

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Decrease of serum levels of the anti-inflammatory cytokine interleukin-10 in patients with advanced chronic heart failure

5 July 2018

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IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3'-kinase

5 July 2018

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Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

5 July 2018

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Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

5 July 2018

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

5 July 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

5 July 2018

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Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

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Normal and abnormal consequences of apoptosis in the human heart. From postnatal morphogenesis to paroxysmal arrhythmias

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IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes.

5 July 2018

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IL-10 attenuates TNF-alpha-induced NF kappaB pathway activation and cardiomyocyte apoptosis

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p38 and ERK1/2 MAPKs mediate the interplay of TNF-alpha and IL-10 in regulating oxidative stress and cardiac myocyte apoptosis

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Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted TNF overexpression.

21 January 2018

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Significance of changes in TNF-alpha and IL-10 levels in the progression of heart failure subsequent to myocardial infarction.

21 January 2018

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Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo

21 January 2018

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Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway.

21 January 2018

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Substitutions of potentially phosphorylatable serine residues of Bax reveal how they may regulate its interaction with mitochondria

21 January 2018

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Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

21 January 2018

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Is tumor necrosis factor an important neurohormonal mechanism in chronic heart failure?

21 January 2018

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12 December 2020

Interplay of TNF-alpha and IL-10 in regulating oxidative stress in isolated adult cardiac myocytes

1 reference

12 December 2020

JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes

1 reference

12 December 2020

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

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12 December 2020

Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase

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12 December 2020

Effect of interleukin-10 on the production of tumor necrosis factor-alpha by peripheral blood mononuclear cells from patients with chronic heart failure

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12 December 2020

Clinical trials update: RENEWAL (RENAISSANCE and RECOVER) and ATTACH

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12 December 2020

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

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12 December 2020

10.1371/JOURNAL.PONE.0025009

Identifiers

DOI

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30 July 2017

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30 July 2017

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