(Q34040991)

30 July 2017

HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines (English)

1 reference

30 July 2017

1 reference

5

Jessica Zucman-Rossi

0 references

Paulette Bioulac-Sage

4

Paulette Bioulac-Sage

0 references

Sandra Rebouissou

Sandra Rebouissou

2

0 references

Danijela Matic Vignjevic

Danijela Vignjevic

3

0 references

Laura Pelletier

1

Laura Pelletier

1 reference

PubMed ID

21975049

30 July 2017

language of work or name

English

0 references

publication date

5 October 2011

1 reference

30 July 2017

1 reference

30 July 2017

11

1 reference

30 July 2017

427

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-11-427

30 July 2017

0 references

cites work

Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Loss of hepatocyte nuclear factor 1alpha function in human hepatocellular adenomas leads to aberrant activation of signaling pathways involved in tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Mechanisms of liver development: concepts for understanding liver disorders and design of novel therapies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Plasticity and expanding complexity of the hepatic transcription factor network during liver development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Complex networks orchestrate epithelial-mesenchymal transitions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Molecular requirements for epithelial-mesenchymal transition during tumor progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Transcriptional regulation of cadherins during development and carcinogenesis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Control of pancreas and liver gene expression by HNF transcription factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Epithelial-mesenchymal transitions in development and pathologies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Positive regulation of connexin32 transcription by hepatocyte nuclear factor-1alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Bi-allelic inactivation of TCF1 in hepatic adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

The snail superfamily of zinc-finger transcription factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Phenotypic effects of the forced expression of HNF4 and HNF1alpha are conditioned by properties of the recipient cell.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Tissue-Specific Regulation of Mouse Hepatocyte Nuclear Factor 4 Expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Liver adenomatosis. An entity distinct from liver adenoma?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

A transcriptional hierarchy involved in mammalian cell-type specification

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Two members of an HNF1 homeoprotein family are expressed in human liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Liver-Cell Adenomas Associated with Use of Oral Contraceptives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Hepatocyte nuclear factor-1 alpha gene inactivation: cosegregation between liver adenomatosis and diabetes phenotypes in two maturity-onset diabetes of the young (MODY)3 families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Germline hepatocyte nuclear factor 1alpha and 1beta mutations in renal cell carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Variant HNF1 modulates epithelial plasticity of normal and transformed ovary cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

Control of hepatic differentiation by activin/TGFbeta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203860

Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC

28 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-427

GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation

21 January 2018

1 reference

12 December 2020

Familial liver adenomatosis associated with hepatocyte nuclear factor 1alpha inactivation

1 reference

12 December 2020

Modulation of Hepatic Gene Expression by Hepatocyte Nuclear Factor 1

1 reference

12 December 2020

A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes

1 reference

12 December 2020

Snail controls differentiation of hepatocytes by repressing HNF4α expression

1 reference

12 December 2020

Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-11-427

1 reference

PubMed ID

21975049

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

21975049