(Q34042921)

30 July 2017

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title

Ceramide and sphingomyelinases in the regulation of stress responses (English)

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30 July 2017

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Sawai H

1

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30 July 2017

Hannun YA

series ordinal

2

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30 July 2017

publication date

1 November 1999

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Chemistry and Physics of Lipids

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

1-2

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30 July 2017

page(s)

141-147

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Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

30 July 2017

cites work

1 reference

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Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

7 January 2021

1 reference

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CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.

7 January 2021

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Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest

7 January 2021

1 reference

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Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway

7 January 2021

1 reference

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p53-dependent ceramide response to genotoxic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Purification of a newly identified alkaline sphingomyelinase in human bile and effects of bile salts and phosphatidylcholine on enzyme activity

7 January 2021

1 reference

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Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics

7 January 2021

1 reference

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Purification and characterization of ceramide-activated protein phosphatases

7 January 2021

1 reference

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Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

7 January 2021

1 reference

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Functions of ceramide in coordinating cellular responses to stress

7 January 2021

1 reference

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Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses

7 January 2021

1 reference

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Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

7 January 2021

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Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

7 January 2021

1 reference

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Role for ceramide in cell cycle arrest.

7 January 2021

1 reference

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Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Evidence that ceramide selectively inhibits protein kinase C-alpha translocation and modulates bradykinin activation of phospholipase D.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Acid sphingomyelinase is not essential for the IL-1 and tumor necrosis factor receptor signaling pathway leading to NFkB activation

7 January 2021

1 reference

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Ceramide inactivates cellular protein kinase Calpha

7 January 2021

1 reference

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Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M.

7 January 2021

1 reference

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Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

7 January 2021

1 reference

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Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

7 January 2021

1 reference

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Purification and characterization of a membrane bound neutral pH optimum magnesium-dependent and phosphatidylserine-stimulated sphingomyelinase from rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha

7 January 2021

1 reference

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KSR stimulates Raf-1 activity in a kinase-independent manner

7 January 2021

1 reference

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Programmed cell death induced by ceramide

7 January 2021

1 reference

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Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation

7 January 2021

1 reference

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Acid sphingomyelinase from human urine: purification and characterization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Isolation of cDNA clones encoding human acid sphingomyelinase: occurrence of alternatively processed transcripts

7 January 2021

1 reference

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c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Requirement of AP-1 for Ceramide-induced Apoptosis in Human Leukemia HL-60 Cells

7 January 2021

1 reference

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Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases

7 January 2021

1 reference

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prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Ceramide inhibits phospholipase D in a cell-free system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Ceramide activates the stress-activated protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Bcl-2 interrupts the ceramide-mediated pathway of cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Kinase suppressor of Ras is ceramide-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-3084%2899%2900082-1

10.1016/S0009-3084(99)00082-1

7 January 2021

Identifiers

DOI

1 reference

30 July 2017

1 reference