(Q34042934)

30 July 2017

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title

Sphingomyelin-degrading pathways in human cells role in cell signalling (English)

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ORCID Public Data File 2021

30 July 2017

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author name string

Levade T

1

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30 July 2017

Andrieu-Abadie N

2

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30 July 2017

Ségui B

3

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30 July 2017

Augé N

4

1 reference

30 July 2017

Chatelut M

5

1 reference

30 July 2017

Jaffrézou JP

6

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30 July 2017

Salvayre R

7

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30 July 2017

publication date

1 November 1999

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Chemistry and Physics of Lipids

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

1-2

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30 July 2017

page(s)

167-178

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Administration of pyrene lipids by receptor-mediated endocytosis and their degradation in skin fibroblasts

30 July 2017

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7 January 2021

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Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts

7 January 2021

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Low Temperatures and Hypertonicity Do Not Block Cytokine-induced Stimulation of the Sphingomyelin Pathway but Inhibit Nuclear Factor-κB Activation

7 January 2021

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Comparative study of the metabolic pools of sphingomyelin and phosphatidylcholine sensitive to tumor necrosis factor

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The tumour necrosis factor-sensitive pool of sphingomyelin is resynthesized in a distinct compartment of the plasma membrane

7 January 2021

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The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation

7 January 2021

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Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein

7 January 2021

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7 January 2021

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7 January 2021

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CD28 signals through acidic sphingomyelinase

7 January 2021

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7 January 2021

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Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies

7 January 2021

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Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue

7 January 2021

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Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

7 January 2021

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Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells

7 January 2021

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Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines

7 January 2021

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Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors

7 January 2021

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Occurrence of two molecular forms of human acid sphingomyelinase

7 January 2021

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Lysosomal localization of sphingomyelinase in rat liver

7 January 2021

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Niemann Pick disease: presence of the magnesium-dependent sphingomyelinase in brain of the infantile form of the disease

7 January 2021

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Magnesium-dependent sphingomyelinase

7 January 2021

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Accurate differentiation of neuronopathic and nonneuronopathic forms of Niemann-Pick disease by evaluation of the effective residual lysosomal sphingomyelinase activity in intact cells.

7 January 2021

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Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells

7 January 2021

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Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation

7 January 2021

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Functions of ceramide in coordinating cellular responses to stress

7 January 2021

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Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

7 January 2021

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Trafficking of glycosphingolipids in eukaryotic cells; sorting and recycling of lipids

7 January 2021

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Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

7 January 2021

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Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase

7 January 2021

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A Novel Enzyme That Cleaves the N-Acyl Linkage of Ceramides in Various Glycosphingolipids as Well as Sphingomyelin to Produce Their Lyso Forms

7 January 2021

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Lipoprotein structure and metabolism

7 January 2021

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Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

7 January 2021

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Sphingomyelin and derivatives as cellular signals

7 January 2021

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Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts

7 January 2021

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Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts

7 January 2021

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Intracellular transport and metabolism of sphingomyelin

7 January 2021

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Uptake and metabolism of radioactively labeled sphingomyelin in cultured skin fibroblasts from controls and patients with Niemann-Pick disease and other lysosomal storage diseases

7 January 2021

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Acid sphingomyelinase is not essential for the IL-1 and tumor necrosis factor receptor signaling pathway leading to NFkB activation

7 January 2021

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Uptake and intracellular degradation of fluorescent sphingomyelin by fibroblasts from normal individuals and a patient with Niemann-Pick disease

7 January 2021

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Comparative hydrolysis of sphingomyelin and 2-N-(hexadecanoyl)-amino-4-nitrophenyl-phosphorylcholine by normal human brain homogenate at acid and neutral pH

7 January 2021

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Evidence for both endogenous and exogenous sources of the sphingomyelin storage in lymphoid cell lines from patients with Niemann-Pick disease types A and B.

7 January 2021

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Uptake and degradation of several pyrenesphingomyelins by skin fibroblasts from control subjects and patients with Niemann-Pick disease. Effect of the structure of the fluorescent fatty acyl residue

7 January 2021

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Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway

7 January 2021

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Compartmentalized Production of Ceramide at the Cell Surface

7 January 2021

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In situ degradation of sphingomyelin by cultured normal fibroblasts and fibroblasts from patients with Niemann-Pick disease type A and C

7 January 2021

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Impairment of exogenous sphingomyelin degradation in cultured fibroblasts from familial hypercholesterolemia

7 January 2021

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An update of the enzymology and regulation of sphingomyelin metabolism

7 January 2021

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Saposin D: a sphingomyelinase activator

7 January 2021

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The presence of sphingomyelin- and ceramide-cleaving enzymes in the small intestinal tract

7 January 2021

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Identification of an alkaline sphingomyelinase activity in human bile

7 January 2021

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Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease)

7 January 2021

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The role of sphingolipids in the process of signal transduction

7 January 2021

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Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

7 January 2021

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Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

7 January 2021

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Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development

7 January 2021

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TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

7 January 2021

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Ceramide 1-phosphate phosphatase activity in brain

7 January 2021

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Acid and neutral sphingomyelinases of rat brain. Activity in developing brain and regional distribution in adult brain

7 January 2021

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Sphingolipid metabolism and cell growth regulation.

7 January 2021

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Signal transduction through lipid second messengers

7 January 2021

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Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice

7 January 2021

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Lysosomal involvement in cellular turnover of plasma membrane sphingomyelin

7 January 2021

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Existence of Mg2+-dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells

7 January 2021

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Sphingomyelin breakdown and cell fate

7 January 2021

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Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

7 January 2021

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Biochemical studies in Niemann-Pick disease. III. In vitro and in vivo assays of sphingomyelin degradation in cultured skin fibroblasts and amniotic fluid cells for the diagnosis of the various forms of the disease

7 January 2021

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I-cell disease: activities of lysosomal enzymes toward natural and synthetic substrates

7 January 2021

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Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.

7 January 2021

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Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts

7 January 2021

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10.1016/S0009-3084(99)00085-7

7 January 2021

Identifiers

DOI

1 reference

30 July 2017

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