(Q34044406)

30 July 2017

title

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo (English)

1 reference

30 July 2017

3

James P Allison

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author name string

Rachel A Gottschalk

series ordinal

1

1 reference

30 July 2017

Emily Corse

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

26 July 2010

1 reference

Journal of Experimental Medicine

30 July 2017

published in

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30 July 2017

volume

207

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30 July 2017

issue

8

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30 July 2017

page(s)

1701-1711

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Attenuated T cell responses to a high-potency ligand in vivo

30 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

5 July 2018

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T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

5 July 2018

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5 July 2018

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All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

5 July 2018

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5 July 2018

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5 July 2018

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TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

5 July 2018

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5 July 2018

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Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

5 July 2018

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Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes

5 July 2018

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CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

5 July 2018

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

5 July 2018

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Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

5 July 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

5 July 2018

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The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4+ T Cells

5 July 2018

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Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

5 July 2018

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

5 July 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

5 July 2018

1 reference

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Control of regulatory T cell development by the transcription factor Foxp3

5 July 2018

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5 July 2018

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Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

5 July 2018

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

5 July 2018

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Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen

5 July 2018

1 reference

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Immunogenicity. I. Use of peptide libraries to identify epitopes that activate clonotypic CD4+ T cells and induce T cell responses to native peptide ligands

5 July 2018

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Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

5 July 2018

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Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Altered T cell receptor ligands trigger a subset of early T cell signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Ligand recognition by alpha beta T cell receptors

5 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916126

Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

28 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Foxp3-dependent programme of regulatory T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091999

Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding

21 January 2018

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

1 reference

12 December 2020

Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression

1 reference

12 December 2020

Origin of regulatory T cells with known specificity for antigen

1 reference

12 December 2020

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

12 December 2020

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

12 December 2020

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta

1 reference

12 December 2020

Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091999

1 reference

30 July 2017

1 reference

30 July 2017

1 reference